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GO:0048017

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description Inositol lipid-mediated signaling
Full defintion A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.
Subterm of

Relationships

The relationship of GO:0048017 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0048017, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCceb
PMID
Nuclear inositol lipid metabolism: more than just second messenger generation?Martelli AM, Follo MY, Evangelisti C, Falà F, Fiume R, Billi AM, Cocco L
J Cell Biochem. 2005 Oct 1; 96 (2): 285–92.PMID: 16088939

A distinct polyphosphoinositide cycle is present in the nucleus, and growing evidence suggests its importance in DNA replication, gene transcription, and apoptosis. Even though it was initially thought that nuclear inositol lipids would function as a source for second messengers, recent findings strongly indicate that lipids present in the nucleus also fulfil other roles. The scope of this review is to highlight the most intriguing advances made in the field over the last few years, such as the possibility that nuclear phosphatidylinositol (4,5) bisphosphate is involved in maintaining chromatin in a transcriptionally active conformation, the new emerging roles for intranuclear phosphatidylinositol (3,4,5) trisphosphate and phosphoinositide 3-kinase, and the evidence which suggests a tight relationship between a decreased level of nuclear phosphoinositide specific phospholipase C-beta1 and the evolution of myelodisplastic syndrome into acute myeloid leukemia.

Associated Lotus transcripts 4

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
LotjaGi5g1v0226900.1
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|V7BGF2|V7BGF2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi5g1v0226900
GO terms
3
LotjaGi6g1v0252900.1
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|I1MGP5|I1MGP5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0252900
GO terms
3
LotjaGi6g1v0252900.2
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|A0A0B2QY87|A0A0B2QY87_GLYSO Phospholipase D p1; Found in the gene: LotjaGi6g1v0252900
GO terms
3
LotjaGi6g1v0252900.3
– Phospholipase D; TAIR: AT3G16785.1 phospholipase D P1; Swiss-Prot: sp|Q9LRZ5|PLDZ1_ARATH Phospholipase D zeta 1; TrEMBL-Plants: tr|A0A0B2QY87|A0A0B2QY87_GLYSO Phospholipase D p1; Found in the gene: LotjaGi6g1v0252900
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0048017
Biological process Inositol lipid-mediated signaling 1 25.00