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GO:0070461

Overview

Field Value
Namespace Cellular component
Short description SAGA-type complex
Full defintion A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins.
Subterm of

Relationships

The relationship of GO:0070461 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0070461, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCmah
PMID
Multi-tasking on chromatin with the SAGA coactivator complexes.
Mutat Res. ; 618 (1-2): 135–48.PMID: 17337012

Over the past 10 years, much progress has been made to understand the roles of the similar, yet distinct yeast SAGA and SLIK coactivator complexes involved in histone post-translational modification and gene regulation. Many different groups have elucidated functions of the SAGA complexes including identification of novel components, which have conferred additional distinct functions. Together, recent studies demonstrate unique attributes of the SAGA coactivator complexes in histone acetylation, methylation, phosphorylation, and deubiquitination. In addition to roles in transcriptional activation with the 19S proteasome regulatory particle, recent evidence also suggests functions for SAGA in elongation and mRNA export. The modular nature of SAGA allows this approximately 1.8 MDa complex to organize its functions and carry out multiple roles during transcription, particularly under conditions of cellular stress.

Associated Lotus transcripts 13

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Uncharacterized protein TCM_036818 [Theobroma cacao] gi|508781959|gb|EOY29215.1| 1
Uncharacterized protein TCM_036818 [Theobroma cacao] gi|508781959|gb|EOY29215.1| 1
Uncharacterized protein TCM_036818 [Theobroma cacao] gi|508781959|gb|EOY29215.1| 1
Uncharacterized protein TCM_000763 [Theobroma cacao] gi|508699743|gb|EOX91639.1| 1
Uncharacterized protein TCM_000763 [Theobroma cacao] gi|508699743|gb|EOX91639.1| 1
Uncharacterized protein TCM_007200 [Theobroma cacao] gi|508706537|gb|EOX98433.1| 1
Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|A6QR06|TADA1_BOVIN Transcriptional adapter 1; TrEMBL-Plants: tr|I1K940|I1K940_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0393800 1
Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|A6QR06|TADA1_BOVIN Transcriptional adapter 1; TrEMBL-Plants: tr|I1K940|I1K940_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0393800 1
Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|A6QR06|TADA1_BOVIN Transcriptional adapter 1; TrEMBL-Plants: tr|I1K940|I1K940_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0393800 1
Transcriptional adapter 1; TAIR: AT2G14850.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q6NWA8|TADA1_DANRE Transcriptional adapter 1; TrEMBL-Plants: tr|K7KPE5|K7KPE5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0096600 1
Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q12060|HFI1_YEAST Transcriptional coactivator HFI1/ADA1; TrEMBL-Plants: tr|I1M9S8|I1M9S8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0066300 1
Transcriptional adapter 1; TAIR: AT2G24530.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q12060|HFI1_YEAST Transcriptional coactivator HFI1/ADA1; TrEMBL-Plants: tr|I1M9S8|I1M9S8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0066300 1
Transcriptional adapter 1; TAIR: AT4G33890.1 transcriptional regulator of RNA polII, SAGA, subunit; Swiss-Prot: sp|Q6DEW4|TADA1_XENTR Transcriptional adapter 1; TrEMBL-Plants: tr|A0A0L9U0A8|A0A0L9U0A8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0323700 1

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Cellular component SAGA-type complex 1 7.69