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Field | Value |
---|---|
Namespace | Biological process |
Short description | Regulation of defense response to fungus |
Full defintion | Any process that modulates the frequency, rate or extent of defense response to fungus. |
Subterm of |
The relationship of GO:1900150 with other GO terms.
Relationship type | GO terms |
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Is a | |
Regulates | |
Part of | n.a. |
Positively regulates | n.a. |
Negatively regulates | n.a. |
A force layout showing the ancestor tree for GO:1900150, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.
This table contains additional metadata associated with the GO entry's definition field.
Field | Value |
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GOC | TermGenie |
PMID | The RNA silencing enzyme RNA polymerase v is required for plant immunity. PLoS Genet. 2011 Dec; 7 (12): e1002434.PMID: 22242006 RNA-directed DNA methylation (RdDM) is an epigenetic control mechanism driven by small interfering RNAs (siRNAs) that influence gene function. In plants, little is known of the involvement of the RdDM pathway in regulating traits related to immune responses. In a genetic screen designed to reveal factors regulating immunity in Arabidopsis thaliana, we identified NRPD2 as the OVEREXPRESSOR OF CATIONIC PEROXIDASE 1 (OCP1). NRPD2 encodes the second largest subunit of the plant-specific RNA Polymerases IV and V (Pol IV and Pol V), which are crucial for the RdDM pathway. The ocp1 and nrpd2 mutants showed increases in disease susceptibility when confronted with the necrotrophic fungal pathogens Botrytis cinerea and Plectosphaerella cucumerina. Studies were extended to other mutants affected in different steps of the RdDM pathway, such as nrpd1, nrpe1, ago4, drd1, rdr2, and drm1drm2 mutants. Our results indicate that all the mutants studied, with the exception of nrpd1, phenocopy the nrpd2 mutants; and they suggest that, while Pol V complex is required for plant immunity, Pol IV appears dispensable. Moreover, Pol V defective mutants, but not Pol IV mutants, show enhanced disease resistance towards the bacterial pathogen Pseudomonas syringae DC3000. Interestingly, salicylic acid (SA)-mediated defenses effective against PsDC3000 are enhanced in Pol V defective mutants, whereas jasmonic acid (JA)-mediated defenses that protect against fungi are reduced. Chromatin immunoprecipitation analysis revealed that, through differential histone modifications, SA-related defense genes are poised for enhanced activation in Pol V defective mutants and provide clues for understanding the regulation of gene priming during defense. Our results highlight the importance of epigenetic control as an additional layer of complexity in the regulation of plant immunity and point towards multiple components of the RdDM pathway being involved in plant immunity based on genetic evidence, but whether this is a direct or indirect effect on disease-related genes is unclear. |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
Transcript | Name | Description | GO terms | GO count |
---|---|---|---|---|
– | Extra-large G-like protein, putative (DUF3133); TAIR: AT5G05190.1 hypothetical protein (DUF3133); Swiss-Prot: sp|Q9FHK4|EDR4_ARATH Protein ENHANCED DISEASE RESISTANCE 4; TrEMBL-Plants: tr|A0A0R0GSC0|A0A0R0GSC0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0131000 | 1 | ||
– | Extra-large G-like protein, putative (DUF3133); TAIR: AT5G05190.1 hypothetical protein (DUF3133); Swiss-Prot: sp|Q9FHK4|EDR4_ARATH Protein ENHANCED DISEASE RESISTANCE 4; TrEMBL-Plants: tr|A0A151SG48|A0A151SG48_CAJCA Uncharacterized protein family; Found in the gene: LotjaGi1g1v0305300 | 1 | ||
– | Extra-large G-like protein; TAIR: AT3G61670.1 extra-large G-like protein, putative (DUF3133); Swiss-Prot: sp|O80462|XLG1_ARATH Extra-large guanine nucleotide-binding protein 1; TrEMBL-Plants: tr|K7KH30|K7KH30_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0791100 | 1 | ||
– | Extra-large G-like protein; TAIR: AT3G61670.1 extra-large G-like protein, putative (DUF3133); Swiss-Prot: sp|O80462|XLG1_ARATH Extra-large guanine nucleotide-binding protein 1; TrEMBL-Plants: tr|K7KH30|K7KH30_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0791100 | 1 | ||
– | Extra-large G-like protein; TAIR: AT3G61670.1 extra-large G-like protein, putative (DUF3133); Swiss-Prot: sp|O80462|XLG1_ARATH Extra-large guanine nucleotide-binding protein 1; TrEMBL-Plants: tr|A0A1J7GVX9|A0A1J7GVX9_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0393100 | 1 |
A list of co-occurring GO terms within the L. japonicus gene space:
GO term | Namespace | Name | Observations | Saturation (%) |
---|---|---|---|---|
Biological process | Regulation of defense response to fungus | 1 | 20.00 |