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IPR000266 is a Small ribosomal subunit protein uS17.
<p>This family includes small ribosomal subunit protein uS17 (formerly known as 30S ribosomal protein S17 and 40S ribosomal protein S11) [[cite:PUB00080279]].</p> <p>The ribosomal proteins catalyse ribosome assembly and stabilise the rRNA, tuning the structure of the ribosome for optimal function. Evidence suggests that, in prokaryotes, the peptidyl transferase reaction is performed by the large subunit 23S rRNA, whereas proteins probably have a greater role in eukaryotic ribosomes. Most of the proteins lie close to, or on the surface of, the 30S subunit, arranged peripherally around the rRNA [[cite:PUB00003381]]. The small subunit ribosomal proteins can be categorised as primary binding proteins, which bind directly and independently to 16S rRNA; secondary binding proteins, which display no specific affinity for 16S rRNA, but its assembly is contingent upon the presence of one or more primary binding proteins; and tertiary binding proteins, which require the presence of one or more secondary binding proteins and sometimes other tertiary binding proteins. The small ribosomal subunit protein uS17 is known to bind specifically to the 5' end of 16S ribosomal RNA in Escherichia coli (primary rRNA binding protein), and is thought to be involved in the recognition of termination codons. Experimental evidence [[cite:PUB00004907]] has revealed that uS17 has virtually no groups exposed on the ribosomal surface.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. | ||
| Cellular component | Ribosome | An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. | ||
| Biological process | Translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: 30S ribosomal protein S17-like isoform 1 [Cucumis sativus] gi|449438751|ref|XP_004137151.1| | 6 | ||
| – | 30S ribosomal protein S17 [Medicago truncatula] gi|357454921|ref|XP_003597741.1| | 15 | ||
| – | 30S ribosomal protein S17 [Medicago truncatula] gi|357495711|ref|XP_003618144.1| | 10 | ||
| – | 40S ribosomal protein S11 [Arabidopsis lyrata subsp]. lyrata] gi|297802956|ref|XP_002869362.1| | 16 | ||
| – | PREDICTED: 40S ribosomal protein S11 [Vitis vinifera] gi|225463039|ref|XP_002267523.1| | 15 | ||
| – | 30S ribosomal S17-like protein; TAIR: AT1G49400.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|B1I1J7|RS17_DESAP 30S ribosomal protein S17; TrEMBL-Plants: tr|I3SZP5|I3SZP5_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0199000 | 11 | ||
| – | 30S ribosomal protein S17; TAIR: AT1G49400.1 Nucleic acid-binding, OB-fold-like protein; Swiss-Prot: sp|B1I1J7|RS17_DESAP 30S ribosomal protein S17; TrEMBL-Plants: tr|I3S3D8|I3S3D8_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0014700 | 11 | ||
| – | 30S ribosomal protein S17; TAIR: AT5G23740.1 ribosomal protein S11-beta; Swiss-Prot: sp|P17093|RS11_SOYBN 40S ribosomal protein S11; TrEMBL-Plants: tr|I3TA88|I3TA88_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0282000 | 14 | ||
| – | 30S ribosomal protein S17; TAIR: AT5G23740.1 ribosomal protein S11-beta; Swiss-Prot: sp|Q9M5M1|RS11_EUPES 40S ribosomal protein S11; TrEMBL-Plants: tr|I3SEW9|I3SEW9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0347800 | 14 | ||
| – | 30S ribosomal protein S17; TAIR: AT5G23740.1 ribosomal protein S11-beta; Swiss-Prot: sp|Q9M5M1|RS11_EUPES 40S ribosomal protein S11; TrEMBL-Plants: tr|I3SEW9|I3SEW9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi5g1v0348100 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR03630 | TIGRFAM | 1 | 10.00 |