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IPR000415 is a Nitroreductase-like.
<p>This domain superfamily is characteristic of nitroreductase enzymes and related oxidoreductases. Members of this family utilise FMN as a cofactor and are often found to be homodimers. Possible characteristics include Oxygen-insensitive NAD(P)H nitroreductase (FMN-dependent nitroreductase) (Dihydropteridine reductase) ([ec:1.5.1.34]) and NADH dehydrogenase ([ec:7.1.1.2]). A number of the proteins are described as oxidoreductases. They are primarily found in bacterial lineages, though a number of eukaryotic homologues have been identified: Caenorhabditis elegans [swissprot:P34273], Drosophila melanogaster (Fruit fly) [swissprot:Q8T3Q0] [swissprot:Q9VTE7], Mus musculus (Mouse) [swissprot:Q9DCX8] and Homo sapiens (Human) [swissprot:O75989]. This protein is not found in photosynthetic eukaryotes. The sequences containing this entry in photosynthetic organisms are possible false positives.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Nitroreductase family protein isoform 1 [Theobroma cacao] gi|508725160|gb|EOY17057.1| | 15 | ||
| – | Nitroreductase family protein isoform 2 [Theobroma cacao] gi|508725161|gb|EOY17058.1| | 15 | ||
| – | Nitroreductase family protein isoform 1 [Theobroma cacao] gi|508725160|gb|EOY17057.1| | 9 | ||
| – | Nitroreductase family protein; TAIR: AT1G02020.1 nitroreductase family protein; Swiss-Prot: sp|Q58779|Y1384_METJA Putative nitroreductase MJ1384; TrEMBL-Plants: tr|G7JFV6|G7JFV6_MEDTR Nitroreductase family protein; Found in the gene: LotjaGi3g1v0436200 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 25.00 |