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IPR000979 is a Phosphodiesterase MJ0936/Vps29.
<p>Members of this largely uncharacterised family share a motif approximating DXH(X25)GDXXD(X25)GNHD as found in several phosphoesterases, including the nucleases SbcD and Mre11, and a family of uncharacterised archaeal putative phosphoesterases. In this family, the His residue in GNHD portion of the motif is not conserved. The member MJ0936, one of two from Methanocaldococcus jannaschii (Methanococcus jannaschii), was shown [[cite:PUB00015606]] to act on model phosphodiesterase substrates; a divalent cation was required. This entry also represents Vps29 which is part of the retromer complex in yeast [[cite:PUB00027771]].</p> <p>This entry also includes vacuolar protein sorting-associated protein 29 (vps29), which is an essential component of the retromer complex, a conserved complex required in endosome-to-Golgi retrograde transport [[cite:PUB00016030]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Vacuolar protein sorting [Medicago truncatula] gi|357493205|ref|XP_003616891.1| | 9 | ||
| – | PREDICTED: vacuolar protein sorting-associated protein 29-like [Cicer arietinum] gi|502134242|ref|XP_004502048.1| | 5 | ||
| – | Vacuolar protein sorting [Medicago truncatula] gi|357493205|ref|XP_003616891.1| | 9 | ||
| – | Vacuolar protein sorting-associated protein 29; TAIR: AT3G47810.1 Calcineurin-like metallo-phosphoesterase superfamily protein; Swiss-Prot: sp|Q9STT2|VPS29_ARATH Vacuolar protein sorting-associated protein 29; TrEMBL-Plants: tr|I3SDN8|I3SDN8_LOTJA Vacuolar protein sorting-associated protein 29; Found in the gene: LotjaGi4g1v0376200 | 11 | ||
| – | Vacuolar protein sorting-associated protein 29; TAIR: AT3G47810.1 Calcineurin-like metallo-phosphoesterase superfamily protein; Swiss-Prot: sp|Q9STT2|VPS29_ARATH Vacuolar protein sorting-associated protein 29; TrEMBL-Plants: tr|I3SDN8|I3SDN8_LOTJA Vacuolar protein sorting-associated protein 29; Found in the gene: LotjaGi4g1v0376200 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd07394 | CDD | 1 | 20.00 |