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IPR001675 is a Glycosyl transferase family 29.
<p>Glycosyltransferase family 29 ([cazy:GT29]) comprises enzymes with a number of known activities; sialyltransferase ([ec:2.4.99]), beta-galactosamide alpha-2,6-sialyltransferase ([ec:2.4.99.1]), alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase ([ec:2.4.99.3]), beta-galactoside alpha-2,3-sialyltransferase ([ec:2.4.99.4]), N-acetyllactosaminide alpha-2,3-sialyltransferase ([ec:2.4.99.6]), alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase ([ec:2.4.99.8]); lactosylceramide alpha-2,3-sialyltransferase ([ec:2.4.99.9]). These enzymes use a nucleotide monophosphosugar as the donor (CMP-NeuA) instead of a nucleotide diphosphosugar.</p> <p>The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates ([ec:2.4.1.-]) and related proteins into distinct sequence based families has been described [[cite:PUB00009409]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and therefore form 'clans'.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Protein glycosylation | A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins. | ||
| Molecular function | Sialyltransferase activity | Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1-like [Cicer arietinum] gi|502145760|ref|XP_004506165.1| | 4 | ||
| – | PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2-like [Cicer arietinum] gi|502106840|ref|XP_004493073.1| | 4 | ||
| – | PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2-like [Cicer arietinum] gi|502106840|ref|XP_004493073.1| | 8 | ||
| – | PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1-like [Cicer arietinum] gi|502145760|ref|XP_004506165.1| | 9 | ||
| – | Sialyltransferase-like protein [Lotus japonicus] gi|83318896|emb|CAJ15148.2| | 10 | ||
| – | Sialyltransferase-like protein [Lotus japonicus] gi|83318896|emb|CAJ15148.2| | 4 | ||
| – | Sialyltransferase-like protein [Lotus japonicus] gi|83318896|emb|CAJ15148.2| | 10 | ||
| – | Sialyltransferase-like protein 2; TAIR: AT1G08660.1 MALE GAMETOPHYTE DEFECTIVE 2; Swiss-Prot: sp|Q8VZJ0|SIA1_ARATH Sialyltransferase-like protein 1; TrEMBL-Plants: tr|K7MXM5|K7MXM5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0632600 | 9 | ||
| – | Sialyltransferase-like protein 2; TAIR: AT1G08280.1 Glycosyltransferase family 29 (sialyltransferase) family protein; Swiss-Prot: sp|Q9SGD2|GT29A_ARATH Beta-1,6-galactosyltransferase GALT29A; TrEMBL-Plants: tr|A0A1J7GYD4|A0A1J7GYD4_LUPAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0478200 | 6 | ||
| – | Sialyltransferase-like protein 2; TAIR: AT1G08280.1 Glycosyltransferase family 29 (sialyltransferase) family protein; Swiss-Prot: sp|Q9SGD2|GT29A_ARATH Beta-1,6-galactosyltransferase GALT29A; TrEMBL-Plants: tr|Q4JEZ1|Q4JEZ1_MEDTR CAZy family GT29 glycosyltransferase; Found in the gene: LotjaGi3g1v0478200 | 13 | ||
| – | Sialyltransferase-like protein 2; TAIR: AT3G48820.1 Glycosyltransferase family 29 (sialyltransferase) family protein; Swiss-Prot: sp|Q8RY00|SIA2_ARATH Sialyltransferase-like protein 2; TrEMBL-Plants: tr|Q4JEZ2|Q4JEZ2_LOTJA Sialyltransferase-like protein; Found in the gene: LotjaGi4g1v0420300 | 11 | ||
| – | Sialyltransferase-like protein 2; TAIR: AT3G48820.1 Glycosyltransferase family 29 (sialyltransferase) family protein; Swiss-Prot: sp|Q8RY00|SIA2_ARATH Sialyltransferase-like protein 2; TrEMBL-Plants: tr|Q4JEZ2|Q4JEZ2_LOTJA Sialyltransferase-like protein; Found in the gene: LotjaGi4g1v0420300 | 5 | ||
| – | Sialyltransferase-like protein 2; TAIR: AT3G48820.1 Glycosyltransferase family 29 (sialyltransferase) family protein; Swiss-Prot: sp|Q8RY00|SIA2_ARATH Sialyltransferase-like protein 2; TrEMBL-Plants: tr|Q4JEZ2|Q4JEZ2_LOTJA Sialyltransferase-like protein; Found in the gene: LotjaGi4g1v0420300 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TMhelix | TMHMM | 1 | 7.69 |