Description

IPR002365 is a Terpene synthase, conserved site.

<p>Several enzymes catalyse mechanistically related reactions which involve the highly complex cyclic rearrangement of squalene or its 2,3 oxide. Lanosterol synthase ([ec:5.4.99.7]) (oxidosqualene--lanosterol cyclase) catalyzes the cyclization of (S)-2,3-epoxysqualene to lanosterol, the initial precursor of cholesterol, steroid hormones and vitamin D in vertebrates and of ergosterol in fungi (gene ERG7). Cycloartenol synthase ([ec:5.4.99.8]) (2,3-epoxysqualene--cycloartenol cyclase), is a plant enzyme that catalyzes the cyclization of (S)-2,3-epoxysqualene to cycloartenol, and hopene synthase ([ec:5.4.99]) (squalene--hopene cyclase), is a bacterial enzyme that catalyzes the cyclization of squalene into hopene, a key step in hopanoid (triterpenoid) metabolism. These enzymes are evolutionary related [[cite:PUB00004809]] proteins of about 70 to 85 kD. This highly conserved region is rich in aromatic residues and is located in the C-terminal section.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Associated Lotus transcripts 21

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: