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IPR002650 is a Sulphate adenylyltransferase.
<p>Sulphate adenylyltransferase or ATP-sulfurylase ([ec:2.7.7.4]) forms adenosine 5'-phosphosulphate (APS) from ATP and free sulphate, the first step in the formation of the activated sulphate donor 3'-phosphoadenylylsulphate (PAPS) [[cite:PUB00001859]]. In some cases, it is found in a bifunctional protein in which the other domain, adenosyl phosphosulphate (APS) kinase, catalyses the second and final step, the phosphorylation of APS to PAPS [[cite:PUB00017401]]. The combined ATP sulfurylase/APS kinase may be called PAPS synthase. In some organisms it is used to generate APS from sulfate and ATP, while in others it proceeds in the opposite direction to generate ATP from APS and pyrophosphate. ATP sulfurylase can be a monomer, a homodimer, or a homo-oligomer, depending on the organism. It belongs to a large superfamily of nucleotidyltransferases that includes pantothenate synthetase (PanC), phosphopantetheine adenylyltransferase (PPAT), the amino-acyl tRNA synthetases, and the dissimilatory sulphate adenylyltransferase (sat) of the sulphate reducer Archaeoglobus fulgidus. The enzymes of this family are structurally similar and share a dinucleotide-binding domain. [[cite:PUB00037012], [cite:PUB00025886], [cite:PUB00026390], [cite:PUB00031989], [cite:PUB00079796], [cite:PUB00079797], [cite:PUB00079798], [cite:PUB00079799], [cite:PUB00079800]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Biological process | Sulfate assimilation | The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds. | ||
Molecular function | Sulfate adenylyltransferase (ATP) activity | Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: ATP sulfurylase 2-like [Cicer arietinum] gi|502148790|ref|XP_004507270.1| | 16 | ||
– | PREDICTED: ATP sulfurylase 1, chloroplastic-like [Cicer arietinum] gi|502119550|ref|XP_004496657.1| | 15 | ||
– | ATP sulfurylase (Sulfate adenylyltransferase); TAIR: AT1G19920.1 Pseudouridine synthase/archaeosine transglycosylase-like family protein; Swiss-Prot: sp|Q43870|APS2_ARATH ATP sulfurylase 2; TrEMBL-Plants: tr|I1LWX5|I1LWX5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0272400 | 16 | ||
– | ATP sulfurylase (Sulfate adenylyltransferase); TAIR: AT1G19920.1 Pseudouridine synthase/archaeosine transglycosylase-like family protein; Swiss-Prot: sp|Q43870|APS2_ARATH ATP sulfurylase 2; TrEMBL-Plants: tr|I1LWX5|I1LWX5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0272400 | 15 | ||
– | ATP sulfurylase (Sulfate adenylyltransferase); TAIR: AT3G22890.1 ATP sulfurylase 1; Swiss-Prot: sp|Q9LIK9|APS1_ARATH ATP sulfurylase 1, chloroplastic; TrEMBL-Plants: tr|A0A067ZBF8|A0A067ZBF8_CICAR ATP sulfurylase; Found in the gene: LotjaGi5g1v0308900 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
cd00517 | CDD | 1 | 20.00 |