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IPR002762

Source: InterPro

Description

IPR002762 is a Sirohydrochlorin cobaltochelatase CbiX-like.

<p>This entry represents sirohydrochlorin cobaltochelatase (also known as CbiX), which catalyses the insertion of Co2+ into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. The structure of CbiX from Archaeoglobus fulgidus consists of a central mixed β-sheet flanked by four α-helices, although it is about half the size of other Class II tetrapyrrole chelatases [[cite:PUB00035320]]. The CbiX proteins found in archaea appear to be shorter than those found in eubacteria [[cite:PUB00014361]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0009236
Biological process Cobalamin biosynthetic process The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
Subterm of
GO:0016852
Molecular function Sirohydrochlorin cobaltochelatase activity Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj2g3v0946310.1
– Sirohydrochlorin ferrochelatase [Medicago truncatula] gi|357495765|ref|XP_003618171.1|
Domains
6
LotjaGi2g1v0243400.1
– Sirohydrochlorin ferrochelatase; TAIR: AT1G50170.1 sirohydrochlorin ferrochelatase B; Swiss-Prot: sp|Q84JH7|SIRB_ARATH Sirohydrochlorin ferrochelatase, chloroplastic; TrEMBL-Plants: tr|A0A0B2R6K7|A0A0B2R6K7_GLYSO Sirohydrochlorin ferrochelatase; Found in the gene: LotjaGi2g1v0243400
Domains
12

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd03416 CDD 1 50.00