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IPR003329 is a Acylneuraminate cytidylyltransferase.
<p>Synonym(s): CMP-N-acetylneuraminic acid synthetase</p> <p>Acylneuraminate cytidylyltransferase ([ec:2.7.7.43]) (CMP-NeuAc synthetase) catalyzes the reaction of CTP and NeuAc to form CMP-NeuAc, which is the nucleotide sugar donor used by sialyltransferases [[cite:PUB00008111]]. The outer membrane lipooligosaccharides of some microorganisms contain terminal sialic acid attached to N-acetyllactosamine and so this modification may be important in pathogenesis.</p> <p>This family also includes 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase found in the bacterial genus Shewanella, which is important in the development of the outer cell membrane and converts 3-deoxy-d-manno-octulosonic acid to 8-amino-3,8-dideoxy-d-manno-octulosonic acid (KDO8N) for incorporation into the lipopolysaccharide [[cite:PUB00082311]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: 3-deoxy-manno-octulosonate cytidylyltransferase-like [Glycine max] gi|356543296|ref|XP_003540098.1| | 9 | ||
| – | PREDICTED: 3-deoxy-manno-octulosonate cytidylyltransferase-like [Glycine max] gi|356543296|ref|XP_003540098.1| | 15 | ||
| – | Nucleotide-diphospho-sugar transferases superfamily protein isoform 1 [Theobroma cacao] gi|508721052|gb|EOY12949.1| | 15 | ||
| – | 3-deoxy-manno-octulosonate cytidylyltransferase; TAIR: AT1G53000.1 Nucleotide-diphospho-sugar transferases superfamily protein; Swiss-Prot: sp|Q9C920|KDSB_ARATH 3-deoxy-manno-octulosonate cytidylyltransferase, mitochondrial; TrEMBL-Plants: tr|A0A072VK14|A0A072VK14_MEDTR 3-deoxy-manno-octulosonate cytidylyltransferase; Found in the gene: LotjaGi3g1v0047800_LC | 14 | ||
| – | 3-deoxy-manno-octulosonate cytidylyltransferase; TAIR: AT1G53000.1 Nucleotide-diphospho-sugar transferases superfamily protein; Swiss-Prot: sp|Q9C920|KDSB_ARATH 3-deoxy-manno-octulosonate cytidylyltransferase, mitochondrial; TrEMBL-Plants: tr|A0A072VK14|A0A072VK14_MEDTR 3-deoxy-manno-octulosonate cytidylyltransferase; Found in the gene: LotjaGi3g1v0047800_LC | 14 | ||
| – | 3-deoxy-manno-octulosonate cytidylyltransferase; TAIR: AT1G53000.1 Nucleotide-diphospho-sugar transferases superfamily protein; Swiss-Prot: sp|Q9C920|KDSB_ARATH 3-deoxy-manno-octulosonate cytidylyltransferase, mitochondrial; TrEMBL-Plants: tr|A0A072VK14|A0A072VK14_MEDTR 3-deoxy-manno-octulosonate cytidylyltransferase; Found in the gene: LotjaGi3g1v0047900 | 15 | ||
| – | 3-deoxy-manno-octulosonate cytidylyltransferase; TAIR: AT1G53000.1 Nucleotide-diphospho-sugar transferases superfamily protein; Swiss-Prot: sp|Q9C920|KDSB_ARATH 3-deoxy-manno-octulosonate cytidylyltransferase, mitochondrial; TrEMBL-Plants: tr|A0A072VK14|A0A072VK14_MEDTR 3-deoxy-manno-octulosonate cytidylyltransferase; Found in the gene: LotjaGi3g1v0181300 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd02517 | CDD | 1 | 14.29 |