Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR004545

Source: InterPro

Description

IPR004545 is a PA2G4 family.

<p>Proteins of this family have been identified in a number of species as a nuclear protein with a cell cycle dependence. Various names have been given to members of this family which include cell cycle protein p38-2G4, also known as proliferation-associated protein PA2G4 [[cite:PUB00074549], [cite:PUB00076723]], curved DNA-binding protein [[cite:PUB00074550]], proliferation-associated protein A, and ErbB3-binding protein 1 (Ebp1) [[cite:PUB00049595]]. They constitute the proliferation-associated PA2G4 family, which is structurally homologous to the type II methionine aminopeptidases, but without methionine aminopeptidase activity [[cite:PUB00048899], [cite:PUB00049595]]. ErbB3 binding protein-1 (Ebp1) is a potential regulator of ErbB3 signaling, and is implicated in cell growth, apoptosis and differentiation in many cell types [[cite:PUB00074555], [cite:PUB00074552]].</p> <p>These proteins are classified as non-peptidase homologues in the MEROPS peptidase family M24 (clan MG).</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj0g3v0302799.1
– EBP1 [Ammopiptanthus mongolicus] gi|99083509|gb|ABF66654.1|
Domains
14
Lj0g3v0302799.3
– EBP1 [Ammopiptanthus mongolicus] gi|99083509|gb|ABF66654.1|
Domains
15
Lj0g3v0302799.4
– EBP1 [Ammopiptanthus mongolicus] gi|99083509|gb|ABF66654.1|
Domains
14
LotjaGi3g1v0194700.1
– Methionine aminopeptidase 2; TAIR: AT3G51800.3 metallopeptidase M24 family protein; Swiss-Prot: sp|M1CZC0|EBP1_SOLTU ERBB-3 BINDING PROTEIN 1; TrEMBL-Plants: tr|A0EVX1|A0EVX1_9FABA EBP1; Found in the gene: LotjaGi3g1v0194700
Domains
17
LotjaGi3g1v0194700.2
– Methionine aminopeptidase 2; TAIR: AT3G51800.3 metallopeptidase M24 family protein; Swiss-Prot: sp|M1CZC0|EBP1_SOLTU ERBB-3 BINDING PROTEIN 1; TrEMBL-Plants: tr|A0EVX1|A0EVX1_9FABA EBP1; Found in the gene: LotjaGi3g1v0194700
Domains
17
LotjaGi3g1v0194700.3
– Methionine aminopeptidase 2; TAIR: AT3G51800.3 metallopeptidase M24 family protein; Swiss-Prot: sp|M1CZC0|EBP1_SOLTU ERBB-3 BINDING PROTEIN 1; TrEMBL-Plants: tr|A0EVX1|A0EVX1_9FABA EBP1; Found in the gene: LotjaGi3g1v0194700
Domains
17
LotjaGi3g1v0194800.1
– Methionine aminopeptidase 2; TAIR: AT3G51800.3 metallopeptidase M24 family protein; Swiss-Prot: sp|M1CZC0|EBP1_SOLTU ERBB-3 BINDING PROTEIN 1; TrEMBL-Plants: tr|A0EVX1|A0EVX1_9FABA EBP1; Found in the gene: LotjaGi3g1v0194800
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 14.29