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IPR004655 is a Beta-ketoacyl-[acyl-carrier-protein] synthase III.
<p>Beta-ketoacyl-[acyl-carrier-protein] synthase III (FabH) generally initiates elongation in type II fatty acid synthase systems found in bacteria and plants. It is responsible for producing the multitude of fatty acid structures found in bacterial membranes [[cite:PUB00007690]]. The two members of this subfamily from Bacillus subtilis differ from each other, and from FabH from Escherichia coli, in acyl group specificity. Active site residues include Cys112, His244 and Asn274 of Escherichia coli FabH. Cys-112 is the site of acyl group attachment.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | 3-oxoacyl-[acyl-carrier-protein] synthase activity | Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein]. | ||
| Biological process | Fatty acid biosynthetic process | The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | 3-oxoacyl-[acyl]-carrier-protein] synthase 3; TAIR: AT1G62640.1 3-ketoacyl-acyl carrier protein synthase III; Swiss-Prot: sp|P49244|FABH1_CUPWR 3-oxoacyl-[acyl]-carrier-protein] synthase 3 A, chloroplastic; TrEMBL-Plants: tr|A0A151RJB7|A0A151RJB7_CAJCA Uncharacterized protein; Found in the gene: LotjaGi3g1v0004000 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00830 | CDD | 1 | 100.00 |