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IPR004696 is a Triose phosphate/phosphoenolpyruvate translocator.
<p>Functionally characterised members of the 6-8 TMS Triose-phosphate Transporter (TPT) family are derived from the inner envelope membranes of chloroplasts and non-green plastids of plants. Under normal physiological conditions, chloroplast TPTs mediate a strict antiport of substrates, frequently exchanging an organic three carbon compound phosphate ester for inorganic phosphate (Pi) [[cite:PUB00014833], [cite:PUB00014834]].</p> <p>Normally, a triose-phosphate, 3-phosphoglycerate, or another phosphorylated C3 compound made in the chloroplast during photosynthesis, exits the organelle into the cytoplasm of the plant cell in exchange for Pi. However, experiments with reconstituted translocator in artificial membranes indicate that transport can also occur by a channel-like uniport mechanism with up to 10-fold higher transport rates. Channel opening may be induced by a membrane potential of large magnitude and/or by high substrate concentrations. Non-green plastid and chloroplast carriers, such as those from maize endosperm and root membranes, mediate transport of C3 compounds phosphorylated at carbon atom 2, particularly phosphoenolpyruvate, in exchange for Pi. These are the phosphoenolpyruvate:Pi antiporters (PPT). Glucose-6-P has also been shown to be a substrate of some plastid translocators (GPT). The three types of proteins (TPT, PPT and GPT) are divergent in sequence as well as substrate specificity, but their substrate specificities overlap.</p> <p>TPT paralogues are also present in Saccharomyces cerevisiae, which are functionally uncharacterised.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Cellular component | Integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. | ||
Molecular function | Transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. | ||
Biological process | Transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: phosphoenolpyruvate/phosphate translocator 2, chloroplastic [Vitis vinifera] gi|225457009|ref|XP_002282424.1| | 11 | ||
– | PREDICTED: phosphoenolpyruvate/phosphate translocator 1, chloroplastic-like [Glycine max] gi|356516664|ref|XP_003527013.1| | 12 | ||
– | Phosphate/phosphoenolpyruvate translocator [Medicago truncatula] gi|357495783|ref|XP_003618180.1| | 11 | ||
– | PREDICTED: glucose-6-phosphate/phosphate translocator 1, chloroplastic-like isoform X3 [Cicer arietinum] gi|502128657|ref|XP_004500037.1| | 11 | ||
– | PREDICTED: glucose-6-phosphate/phosphate translocator 2, chloroplastic-like [Glycine max] gi|356548981|ref|XP_003542877.1| | 12 | ||
– | Phosphate translocator; TAIR: AT5G33320.1 Glucose-6-phosphate/phosphate translocator-like protein; Swiss-Prot: sp|Q8RXN3|PPT1_ARATH Phosphoenolpyruvate/phosphate translocator 1, chloroplastic; TrEMBL-Plants: tr|I1KCF1|I1KCF1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0179200 | 12 | ||
– | Phosphoenolpyruvate/phosphate translocator; TAIR: AT3G01550.1 phosphoenolpyruvate (pep)/phosphate translocator 2; Swiss-Prot: sp|Q84QU8|PPT2_ORYSJ Phosphoenolpyruvate/phosphate translocator 2, chloroplastic; TrEMBL-Plants: tr|G7KHI6|G7KHI6_MEDTR Plastid phosphate translocator; Found in the gene: LotjaGi2g1v0243600 | 11 | ||
– | Phosphate translocator; TAIR: AT5G46110.1 Glucose-6-phosphate/phosphate translocator-like protein; Swiss-Prot: sp|P21727|TPT_PEA Triose phosphate/phosphate translocator, chloroplastic; TrEMBL-Plants: tr|I1M068|I1M068_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0061600 | 11 | ||
– | Phosphate translocator; TAIR: AT5G46110.1 Glucose-6-phosphate/phosphate translocator-like protein; Swiss-Prot: sp|P21727|TPT_PEA Triose phosphate/phosphate translocator, chloroplastic; TrEMBL-Plants: tr|I1M068|I1M068_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0061600 | 15 | ||
– | Phosphate translocator; TAIR: AT5G46110.1 Glucose-6-phosphate/phosphate translocator-like protein; Swiss-Prot: sp|P21727|TPT_PEA Triose phosphate/phosphate translocator, chloroplastic; TrEMBL-Plants: tr|I1M068|I1M068_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0061600 | 11 | ||
– | Phosphate translocator; TAIR: AT5G46110.4 Glucose-6-phosphate/phosphate translocator-like protein; Swiss-Prot: sp|P21727|TPT_PEA Triose phosphate/phosphate translocator, chloroplastic; TrEMBL-Plants: tr|I1M068|I1M068_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0061600 | 11 | ||
– | Phosphate translocator; TAIR: AT5G33320.1 Glucose-6-phosphate/phosphate translocator-like protein; Swiss-Prot: sp|Q8RXN3|PPT1_ARATH Phosphoenolpyruvate/phosphate translocator 1, chloroplastic; TrEMBL-Plants: tr|A0A067K4L9|A0A067K4L9_JATCU Uncharacterized protein; Found in the gene: LotjaGi4g1v0232500 | 11 | ||
– | Glucose-6-phosphate/phosphate-translocator; TAIR: AT5G54800.1 glucose 6-phosphate/phosphate translocator 1; Swiss-Prot: sp|Q9M5A9|GPT1_ARATH Glucose-6-phosphate/phosphate translocator 1, chloroplastic; TrEMBL-Plants: tr|A0A151T1B9|A0A151T1B9_CAJCA Uncharacterized protein; Found in the gene: LotjaGi6g1v0162600 | 11 | ||
– | Glucose-6-phosphate/phosphate-translocator; TAIR: AT5G54800.1 glucose 6-phosphate/phosphate translocator 1; Swiss-Prot: sp|Q9M5A9|GPT1_ARATH Glucose-6-phosphate/phosphate translocator 1, chloroplastic; TrEMBL-Plants: tr|A0A151T1B9|A0A151T1B9_CAJCA Uncharacterized protein; Found in the gene: LotjaGi6g1v0162600 | 11 | ||
– | Glucose-6-phosphate/phosphate translocator-like protein; TAIR: AT1G61800.1 glucose-6-phosphate/phosphate translocator 2; Swiss-Prot: sp|Q94B38|GPT2_ARATH Glucose-6-phosphate/phosphate translocator 2, chloroplastic; TrEMBL-Plants: tr|I1M125|I1M125_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0296500 | 12 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
TRANSMEMBRANE | Phobius | 1 | 6.67 |