Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR004971

Source: InterPro

Description

IPR004971 is a mRNA (guanine-N(7))-methyltransferase domain.

<p>This entry represents mRNA (guanine-N(7))-methyltransferase, which can either be found as a single domain protein, or as a domain within the mRNA-capping enzyme catalytic subunit.</p> <p>mRNA (guanine-N(7))-methyltransferase methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. It binds RNA containing 5'-terminal GpppC [[cite:PUB00058114], [cite:PUB00027904], [cite:PUB00058116], [cite:PUB00058117], [cite:PUB00058115], [cite:PUB00058118], [cite:PUB00100699]]. Viral mRNA capping enzymes, meanwhile, are multidomain proteins that catalyse the first two reactions in the mRNA cap formation pathway [[cite:PUB00100699]]. They are heterodimers consisting of a large (catalytic) and small subunit.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 8

Transcript Name Description Predicted domains Domain count
Lj0g3v0010139.1
– PREDICTED: mRNA cap guanine-N7 methyltransferase 2-like [Cicer arietinum] gi|502136285|ref|XP_004502631.1|
Domains
10
Lj0g3v0195589.1
– PREDICTED: mRNA cap guanine-N7 methyltransferase 1-like [Glycine max] gi|356526183|ref|XP_003531699.1|
Domains
11
Lj0g3v0239139.2
– PREDICTED: mRNA cap guanine-N7 methyltransferase 1-like [Cicer arietinum] gi|502171646|ref|XP_004515076.1|
Domains
11
LotjaGi1g1v0283100.1
– MRNA cap guanine-N7 methyltransferase; TAIR: AT3G52210.3 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q5HZ60|MCES2_ARATH mRNA cap guanine-N7 methyltransferase 2; TrEMBL-Plants: tr|V7ASJ5|V7ASJ5_PHAVU Uncharacterized protein; Found in the gene: LotjaGi1g1v0283100
Domains
10
LotjaGi1g1v0339600.1
– MRNA cap guanine-N7 methyltransferase; TAIR: AT3G20650.1 mRNA capping enzyme family protein; Swiss-Prot: sp|Q9LHQ7|MCES1_ARATH mRNA cap guanine-N7 methyltransferase 1; TrEMBL-Plants: tr|A0A151RKT4|A0A151RKT4_CAJCA mRNA cap guanine-N7 methyltransferase; Found in the gene: LotjaGi1g1v0339600
Domains
13
LotjaGi1g1v0339600.2
– MRNA cap guanine-N7 methyltransferase; TAIR: AT3G20650.1 mRNA capping enzyme family protein; Swiss-Prot: sp|Q9LHQ7|MCES1_ARATH mRNA cap guanine-N7 methyltransferase 1; TrEMBL-Plants: tr|A0A151RKT4|A0A151RKT4_CAJCA mRNA cap guanine-N7 methyltransferase; Found in the gene: LotjaGi1g1v0339600
Domains
13
LotjaGi1g1v0339600.3
– MRNA cap guanine-N7 methyltransferase; TAIR: AT3G20650.1 mRNA capping enzyme family protein; Swiss-Prot: sp|Q9LHQ7|MCES1_ARATH mRNA cap guanine-N7 methyltransferase 1; TrEMBL-Plants: tr|A0A151RKT4|A0A151RKT4_CAJCA mRNA cap guanine-N7 methyltransferase; Found in the gene: LotjaGi1g1v0339600
Domains
13
LotjaGi3g1v0095400.1
– MRNA cap guanine-N7 methyltransferase; TAIR: AT3G20650.1 mRNA capping enzyme family protein; Swiss-Prot: sp|Q9LHQ7|MCES1_ARATH mRNA cap guanine-N7 methyltransferase 1; TrEMBL-Plants: tr|K7L7W0|K7L7W0_SOYBN mRNA cap guanine-N7 methyltransferase; Found in the gene: LotjaGi3g1v0095400
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 12.50