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IPR005336

Source: InterPro

Description

IPR005336 is a Mitochondrial pyruvate carrier.

<p>This entry represents the mitochondrial pyruvate carrier proteins, including Mpc 1/2 and their homologues. They mediate the uptake of pyruvate into mitochondria [[cite:PUB00066748]]. In humans, Mpc1 and Mpc2 associate to form an ~150-kilodalton complex in the inner mitochondrial membrane [[cite:PUB00066748]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005743
Cellular component Mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
Subterm of
GO:0006850
Biological process Mitochondrial pyruvate transmembrane transport The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion.
Subterm of

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj1g3v3833920.1
– PREDICTED: brain protein 44-like protein-like [Glycine max] gi|356571499|ref|XP_003553914.1|
Domains
8
Lj5g3v2241260.1
– Uncharacterized protein TCM_014596 [Theobroma cacao] gi|508775169|gb|EOY22425.1|
Domains
7
Lj6g3v1786790.1
– PREDICTED: mitochondrial pyruvate carrier 2-like [Solanum lycopersicum] gi|460409650|ref|XP_004250251.1|
Domains
4
LotjaGi1g1v0620400.1
– Mitochondrial pyruvate carrier; TAIR: AT5G20090.1 Uncharacterized protein family (UPF0041); Swiss-Prot: sp|Q949R9|MPC1_ARATH Mitochondrial pyruvate carrier 1; TrEMBL-Plants: tr|I3T3P0|I3T3P0_LOTJA Mitochondrial pyruvate carrier; Found in the gene: LotjaGi1g1v0620400
Domains
8
LotjaGi5g1v0347200.1
– Mitochondrial pyruvate carrier; TAIR: AT5G20090.1 Uncharacterized protein family (UPF0041); Swiss-Prot: sp|Q949R9|MPC1_ARATH Mitochondrial pyruvate carrier 1; TrEMBL-Plants: tr|I3T207|I3T207_LOTJA Mitochondrial pyruvate carrier; Found in the gene: LotjaGi5g1v0347200
Domains
7
LotjaGi5g1v0347200.2
– Mitochondrial pyruvate carrier; TAIR: AT5G20090.1 Uncharacterized protein family (UPF0041); Swiss-Prot: sp|Q949R9|MPC1_ARATH Mitochondrial pyruvate carrier 1; TrEMBL-Plants: tr|I3T207|I3T207_LOTJA Mitochondrial pyruvate carrier; Found in the gene: LotjaGi5g1v0347200
Domains
7
LotjaGi6g1v0287800.1
– Mitochondrial pyruvate carrier; TAIR: AT4G22310.1 Uncharacterized protein family (UPF0041); Swiss-Prot: sp|O49636|MPC4_ARATH Mitochondrial pyruvate carrier 4; TrEMBL-Plants: tr|I3SBD4|I3SBD4_LOTJA Mitochondrial pyruvate carrier; Found in the gene: LotjaGi6g1v0287800
Domains
4

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR14154:SF57 PANTHER 1 14.29