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IPR005352 is a Erg28.
<p>This is a family of integral membrane proteins, which may contain four transmembrane helices. Members of this family are thought to be involved in sterol C-4 demethylation. In Saccharomyces cerevisiae (Baker's yeast) they may tether Erg26p (sterol dehydrogenase/decarboxylase) and Erg27p (3-ketoreductase) to the endoplasmic reticulum or may facilitate interaction between these proteins [[cite:PUB00019518]]. The family contains a conserved arginine and histidine that may be functionally important.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Ergosterol biosynthetic protein [Medicago truncatula] gi|357466749|ref|XP_003603659.1| | 8 | ||
| – | Ergosterol biosynthetic protein 28; TAIR: AT1G10030.1 ergosterol biosynthesis protein; Swiss-Prot: sp|O80594|ERG28_ARATH Ergosterol biosynthetic protein 28; TrEMBL-Plants: tr|I3SL99|I3SL99_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0410500 | 8 | ||
| – | Ergosterol biosynthetic protein 28; TAIR: AT1G10030.1 ergosterol biosynthesis protein; Swiss-Prot: sp|O80594|ERG28_ARATH Ergosterol biosynthetic protein 28; TrEMBL-Plants: tr|I3SL99|I3SL99_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0410500 | 8 | ||
| – | Ergosterol biosynthetic protein 28; TAIR: AT1G10030.1 ergosterol biosynthesis protein; Swiss-Prot: sp|O80594|ERG28_ARATH Ergosterol biosynthetic protein 28; TrEMBL-Plants: tr|I3SL99|I3SL99_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0410500 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 25.00 |