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IPR005855

Source: InterPro

Description

IPR005855 is a Glucosamine-fructose-6-phosphate aminotransferase, isomerising.

<p>Glucosamine:fructose-6-phosphate aminotransferase (GFAT or GlmS, [ec:2.6.1.16]) catalyses the formation of glucosamine 6-phosphate and is the first and rate-limiting enzyme of the hexosamine biosynthetic pathway. The final product of the hexosamine pathway, UDP-N-acetyl glucosamine, is an active precursor of numerous macromolecules containing amino sugars [[cite:PUB00085441], [cite:PUB00085614]].</p> <p>This family of sequences belong to the MEROPS peptidase family C44 (clan PB(C)), and are classified as non-peptidase homologues.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004360
Molecular function Glutamine-fructose-6-phosphate transaminase (isomerizing) activity Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.
Subterm of
GO:1901137
Biological process Carbohydrate derivative biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj1g3v2838100.1
– PREDICTED: glutamine--fructose-6-phosphate aminotransferase [isomerizing] gi|502105634|ref|XP_004492850.1|
Domains
18
Lj1g3v2838100.2
– PREDICTED: glutamine--fructose-6-phosphate aminotransferase [isomerizing] gi|502105634|ref|XP_004492850.1|
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00