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IPR005861 is a Histidinol-phosphate aminotransferase family.
<p>The histidinol phosphate aminotransferase family consists of class I pyridoxal-5'-phosphate (PLP)-dependent enzymes that catalyze a step of L-histidine biosynthesis [[cite:PUB00056758]]. These proteins are highly specific enzymes in the sense that no other aminotransferases are known to be capable of utilizing imidazoleacetol phosphate, with deletions leading to auxotrophy. A subgroup of these enzymes have broader substrate specificity and are capable of using aromatic amino acid substrates in vitro and in vivo</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Biological process | Histidine biosynthetic process | The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. | ||
| Molecular function | Histidinol-phosphate transaminase activity | Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: histidinol-phosphate aminotransferase, chloroplastic-like [Glycine max] gi|356559575|ref|XP_003548074.1| | 14 | ||
| – | Histidinol-phosphate aminotransferase; TAIR: AT1G71920.2 HISTIDINE BIOSYNTHESIS 6B; Swiss-Prot: sp|B9DHD3|HIS6A_ARATH Histidinol-phosphate aminotransferase 1, chloroplastic; TrEMBL-Plants: tr|A0A151T4W1|A0A151T4W1_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0445800 | 13 | ||
| – | Histidinol-phosphate aminotransferase; TAIR: AT1G71920.2 HISTIDINE BIOSYNTHESIS 6B; Swiss-Prot: sp|Q9FEW2|HIS8_NICPL Histidinol-phosphate aminotransferase, chloroplastic; TrEMBL-Plants: tr|I1MNX6|I1MNX6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0445800 | 14 | ||
| – | Histidinol-phosphate aminotransferase; TAIR: AT1G71920.2 HISTIDINE BIOSYNTHESIS 6B; Swiss-Prot: sp|Q9FEW2|HIS8_NICPL Histidinol-phosphate aminotransferase, chloroplastic; TrEMBL-Plants: tr|A0A151T4W1|A0A151T4W1_CAJCA Uncharacterized protein; Found in the gene: LotjaGi2g1v0445800 | 13 | ||
| – | Histidinol-phosphate aminotransferase; TAIR: AT1G71920.2 HISTIDINE BIOSYNTHESIS 6B; Swiss-Prot: sp|Q9FEW2|HIS8_NICPL Histidinol-phosphate aminotransferase, chloroplastic; TrEMBL-Plants: tr|I1MNX6|I1MNX6_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0445800 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00609 | CDD | 1 | 20.00 |