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IPR005952 is a Phosphoglycerate mutase 1.
<p>Most members of this family are phosphoglycerate mutases ([ec:5.4.2.11]) [[cite:PUB00067071]]. This enzyme interconverts 2-phosphoglycerate and 3-phosphoglycerate. <reaction> 2-phospho-D-glycerate + 2,3-diphosphoglycerate = 3-phospho-D-glycerate + 2,3-diphosphoglycerate.</reaction> The enzyme is transiently phosphorylated on an active site histidine by 2,3-diphosphoglyerate, which is both substrate and product. Some members of this family have phosphoglycerate mutase as a minor activity and act primarily as a bisphoglycerate mutase, interconverting 2,3-diphosphoglycerate and 1,3-diphosphoglycerate ([ec:5.4.2.4]) [[cite:PUB00103832]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Phosphoglycerate mutase activity | Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate. | ||
| Biological process | Glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. | ||
| Molecular function | Intramolecular transferase activity, phosphotransferases | Catalysis of the transfer of a phosphate group from one position to another within a single molecule. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase-like [Glycine max] gi|356548228|ref|XP_003542505.1| | 9 | ||
| – | PREDICTED: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase-like [Glycine max] gi|356508122|ref|XP_003522809.1| | 11 | ||
| – | PREDICTED: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase-like [Glycine max] gi|356508122|ref|XP_003522809.1| | 14 | ||
| – | PREDICTED: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase-like [Glycine max] gi|356511107|ref|XP_003524271.1| | 13 | ||
| – | 12 | |||
| – | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TAIR: AT1G22170.1 Phosphoglycerate mutase family protein; Swiss-Prot: sp|Q6MEW4|GPMA_PARUW 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TrEMBL-Plants: tr|I1JVH1|I1JVH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0147800 | 13 | ||
| – | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TAIR: AT1G22170.1 Phosphoglycerate mutase family protein; Swiss-Prot: sp|Q6MEW4|GPMA_PARUW 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TrEMBL-Plants: tr|I1JVH1|I1JVH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0147800 | 14 | ||
| – | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TAIR: AT1G22170.1 Phosphoglycerate mutase family protein; Swiss-Prot: sp|Q6MEW4|GPMA_PARUW 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TrEMBL-Plants: tr|A0A072UYQ0|A0A072UYQ0_MEDTR Phosphoglycerate/bisphosphoglycerate mutase family protein; Found in the gene: LotjaGi1g1v0245800 | 14 | ||
| – | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TAIR: AT1G22170.1 Phosphoglycerate mutase family protein; Swiss-Prot: sp|Q6MEW4|GPMA_PARUW 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TrEMBL-Plants: tr|I1JVH1|I1JVH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0245800 | 14 | ||
| – | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TAIR: AT1G22170.1 Phosphoglycerate mutase family protein; Swiss-Prot: sp|Q6MEW4|GPMA_PARUW 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TrEMBL-Plants: tr|V7CND9|V7CND9_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0399800 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd07067 | CDD | 1 | 10.00 |