Domain Predictions — View

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IPR006667

Source: InterPro

Description

IPR006667 is a SLC41A/MgtE, integral membrane domain.

<p>This entry represents the integral membrane region of SLC41 transporter proteins. SLC41 family of divalent cation transporters includes SLC41A1/2/3 from eukaryotes and MgtE from prokaryotes [[cite:PUB00098696], [cite:PUB00098704], [cite:PUB00098698], [cite:PUB00098699], [cite:PUB00044725]]. MgtE is the prokaryote homologue of SLC41A1 magnesium transporter which adopts a homodimeric architecture with five transmembrane domains in the C terminus and cytosolic N terminus domains [[cite:PUB00098702], [cite:PUB00044725]]. Bacterial family members have one copy of this region while archaeal and eukaryotic sequences have two.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

GO term	Namespace	Name	Definition	Relationships
GO:0006812 View details of GO:0006812 AmiGO InterPro QuickGO	Biological process	Cation transport	The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	Subterm of GO:0006811
GO:0008324 View details of GO:0008324 AmiGO InterPro QuickGO	Molecular function	Cation transmembrane transporter activity	Enables the transfer of cation from one side of a membrane to the other.	Subterm of GO:0015075

Associated Lotus transcripts 2

Transcript	Name	Description	Predicted domains	Domain count
Lj4g3v1969840.2 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Transmembrane protein [Medicago truncatula] gi\|357478409\|ref\|XP_003609490.1\|	Domains CYTOPLASMIC_DOMAIN G3DSA:1.10.357.20 IPR006667 NON_CYTOPLASMIC_DOMAIN PTHR31414 PTHR31414:SF1 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SignalP-noTM_EUK TMhelix TRANSMEMBRANE	13
Lj4g3v1969840.3 View transcript LORE1 v3.0 Genome browser Expression Atlas (ExpAt)	–	Transmembrane protein [Medicago truncatula] gi\|357478409\|ref\|XP_003609490.1\|	Domains CYTOPLASMIC_DOMAIN G3DSA:1.10.357.20 IPR006667 NON_CYTOPLASMIC_DOMAIN PTHR31414 PTHR31414:SF1 SIGNAL_PEPTIDE SIGNAL_PEPTIDE_C_REGION SIGNAL_PEPTIDE_H_REGION SIGNAL_PEPTIDE_N_REGION SignalP-noTM_EUK TMhelix TRANSMEMBRANE	13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain	Source	Observations	Saturation (%)
TRANSMEMBRANE	Phobius	1	50.00