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IPR007346

Source: InterPro

Description

IPR007346 is a Endonuclease I.

<p>Bacterial periplasmic or secreted ([ec:3.1.21.1]) Escherichia coli endonuclease I (EndoI) is a sequence independent endonuclease located in the periplasm. It is inhibited by different RNA species. It is thought to normally generate double strand breaks in DNA, except in the presence of high salt concentrations and RNA, when it generates single strand breaks in DNA. Its biological role is unknown [[cite:PUB00009914]]. Other family members are known to be extracellular [[cite:PUB00009915]]. This family also includes a non-specific, Mg<sup>2+</sup>-activated ribonuclease precursor ([swissprot:Q03091]) [[cite:PUB00009916]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004518
Molecular function Nuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi4g1v0308900.1
– Extracellular ribonuclease; TAIR: AT1G29310.1 SecY protein transport family protein; Swiss-Prot: sp|Q03091|BSN1_BACAM Extracellular ribonuclease; TrEMBL-Plants: tr|A0A151R300|A0A151R300_CAJCA Extracellular ribonuclease; Found in the gene: LotjaGi4g1v0308900
Domains
4

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF54060 SUPERFAMILY 1 100.00