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IPR008493 is a Hikeshi-like, N-terminal domain.
<p>This entry represents a domain found at the N-terminal of human Hikeshi and its orthologues OPI10 from other eukaryotes. Hikeshi acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress; it acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus [[cite:PUB00075511]]. The N-terminal domain shows a jelly-roll/β-sandwich fold with two layers of β-sheets consisting of three and five and five antiparallel β-strands [[cite:PUB00101203], [cite:PUB00101202]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | OPI10-like protein [Medicago truncatula] gi|357491821|ref|XP_003616198.1| | 10 | ||
| – | OPI10-like protein [Medicago truncatula] gi|357491821|ref|XP_003616198.1| | 6 | ||
| – | Hikeshi-like protein; TAIR: AT1G66080.1 hikeshi-like protein; Swiss-Prot: sp|Q568T4|HIKES_DANRE Protein Hikeshi; TrEMBL-Plants: tr|A0A0L9UWY2|A0A0L9UWY2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0098100 | 4 | ||
| – | Hikeshi-like protein; TAIR: AT1G66080.1 hikeshi-like protein; Swiss-Prot: sp|Q568T4|HIKES_DANRE Protein Hikeshi; TrEMBL-Plants: tr|A0A0L9UWY2|A0A0L9UWY2_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0098100 | 4 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| PTHR12925 | PANTHER | 1 | 25.00 |