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IPR008530 is a Coiled-coil domain-containing protein 22.
<p>Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex [[cite:PUB00077065]]. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer [[cite:PUB00077066]].</p> <p>This entry also includes CCDC22 homologues from animals and plants.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: coiled-coil domain-containing protein 22 homolog [Cicer arietinum] gi|502123684|ref|XP_004498218.1| | 5 | ||
| – | Coiled-coil domain-containing protein 22 like; TAIR: AT1G55830.1 coiled-coil protein; Swiss-Prot: sp|B0WTU5|CCD22_CULQU Coiled-coil domain-containing protein 22 homolog; TrEMBL-Plants: tr|I1N086|I1N086_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0141200 | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 50.00 |