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IPR008775 is a Phytanoyl-CoA dioxygenase-like.
<p>This family includes several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins as well as several bacterial deoxygenases. PhyH is a peroxisomal enzyme catalysing the first step of phytanic acid alpha-oxidation. PhyH deficiency causes Refsum's disease (RD), which is an inherited neurological syndrome biochemically characterised by the accumulation of phytanic acid in plasma and tissues [[cite:PUB00011422]].</p> <p>The bacterial deoxygenase 2-aminoethylphosphonate dioxygenase (PhnY) hydroxylates 2-aminoethylphosphonic acid to form (2-amino-1-hydroxyethyl)phosphonic acid, which is then oxidatively converted to inorganic phosphate and glycine by 2-amino-1-hydroxyethylphosphonate dioxygenase (PhnZ) [[cite:PUB00090978]].</p> <p>Ectoine dioxygenase from Streptomyces coelicolor (EctD) is involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte [[cite:PUB00100770]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: phytanoyl-CoA dioxygenase domain-containing protein 1-like [Glycine max] gi|356575959|ref|XP_003556103.1| | 6 | ||
| – | PREDICTED: phytanoyl-CoA dioxygenase domain-containing protein 1-like [Cicer arietinum] gi|502143285|ref|XP_004505285.1| | 6 | ||
| – | Phytanoyl-CoA dioxygenase domain protein; TAIR: AT2G01490.1 phytanoyl-CoA dioxygenase (PhyH) family protein; Swiss-Prot: sp|Q9ZVF6|PAHX_ARATH Phytanoyl-CoA dioxygenase; TrEMBL-Plants: tr|I3SR87|I3SR87_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0081600 | 6 | ||
| – | Phytanoyl-CoA dioxygenase domain protein; TAIR: AT2G01490.1 phytanoyl-CoA dioxygenase (PhyH) family protein; Swiss-Prot: sp|Q9ZVF6|PAHX_ARATH Phytanoyl-CoA dioxygenase; TrEMBL-Plants: tr|I3SR87|I3SR87_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0081600 | 6 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF51197 | SUPERFAMILY | 1 | 25.00 |