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IPR010164 is a Ornithine aminotransferase.
<p>Ornithine aminotransferase catalyses the conversion of L-ornithine and a 2-oxo acid to L-glutamate 5-semialdehyde and an L-amino acid. This enzyme is found in low-GC bacteria, where it is responsible for the fourth step in arginine biosynthesis, and in the mitochondrial matrix of eukaryotes, where it controls L-ornithine levels in tissues. In human hereditary ornithine aminotransferase deficiency, the elevated levels of intraocular concentrations of ornithine are responsible for gyrate atrophy, which affects the CNS and peripheral nervous system [[cite:PUB00014863]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Ornithine-oxo-acid transaminase activity | Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: ornithine aminotransferase, mitochondrial-like [Cicer arietinum] gi|502141592|ref|XP_004504557.1| | 9 | ||
| – | 9 | |||
| – | PREDICTED: probable ornithine aminotransferase-like, partial [Cucumis sativus] gi|449533799|ref|XP_004173859.1| | 9 | ||
| – | Ornithine-delta-aminotransferase isoform 1 [Theobroma cacao] gi|508780402|gb|EOY27658.1| | 10 | ||
| – | 10 | |||
| – | Ornithine aminotransferase [Glycine max] gi|351727128|ref|NP_001237150.1| | 9 | ||
| – | PREDICTED: ornithine aminotransferase, mitochondrial-like [Cicer arietinum] gi|502141592|ref|XP_004504557.1| | 15 | ||
| – | PREDICTED: ornithine aminotransferase, mitochondrial-like [Cicer arietinum] gi|502141592|ref|XP_004504557.1| | 15 | ||
| – | Aminotransferase like protein; TAIR: AT5G46180.1 ornithine-delta-aminotransferase; Swiss-Prot: sp|Q9FNK4|OAT_ARATH Ornithine aminotransferase, mitochondrial; TrEMBL-Plants: tr|I1KRV5|I1KRV5_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0340700 | 17 | ||
| – | Aminotransferase like protein; TAIR: AT5G46180.1 ornithine-delta-aminotransferase; Swiss-Prot: sp|Q9FNK4|OAT_ARATH Ornithine aminotransferase, mitochondrial; TrEMBL-Plants: tr|B1A0U3|B1A0U3_PEA Ornithine aminotransferase; Found in the gene: LotjaGi4g1v0360800 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd00610 | CDD | 1 | 10.00 |