Description

IPR005814 is a Aminotransferase class-III.

<p>Aminotransferases share certain mechanistic features with other pyridoxalphosphate-dependent enzymes, such as the covalent binding of the pyridoxalphosphate group to a lysine residue. On the basis of sequence similarity, these various enzymes can be grouped into subfamilies [[cite:PUB00002716]]. One of these, called class-III, includes:</p> <ul><li>Acetylornithine aminotransferase ([ec:2.6.1.11]), which catalyses the transfer of an amino group from acetylornithine to alpha-ketoglutarate, yielding N-acetyl-glutamic-5-semi-aldehyde and glutamic acid [[cite:PUB00008007]];</li> <li>Ornithine aminotransferase ([ec:2.6.1.13]), which catalyses the transfer of an amino group from ornithine to alpha-ketoglutarate, yielding glutamic-5-semi-aldehyde and glutamic acid [[cite:PUB00085096]];</li> <li>Omega-amino acid--pyruvate aminotransferase ([ec:2.6.1.18]), which catalyses transamination between a variety of omega-amino acids, mono-and diamines, and pyruvate [[cite:PUB00057659]];</li> <li>4-aminobutyrate aminotransferase ([ec:2.6.1.19]) (GABA transaminase), which catalyses the transfer of an amino group from GABA to alpha-ketoglutarate, yielding succinate semialdehyde and glutamic acid [[cite:PUB00085097]];</li> <li>DAPA aminotransferase ([ec:2.6.1.62]), a bacterial enzyme (bioA), which catalyses an intermediate step in the biosynthesis of biotin, the transamination of 7-keto-8-aminopelargonic acid to form 7,8-diaminopelargonic acid [[cite:PUB00056810]];</li> <li>2,2-dialkylglycine decarboxylase ([ec:4.1.1.64]), a Burkholderia cepacia (Pseudomonas cepacia) enzyme (dgdA) that catalyses the decarboxylating amino transfer of 2,2-dialkylglycine and pyruvate to dialkyl ketone, alanine and carbon dioxide [[cite:PUB00023027]];</li> <li>Glutamate-1-semialdehyde aminotransferase ([ec:5.4.3.8]) (GSA) [[cite:PUB00085098]];</li> <li>Bacillus subtilis aminotransferases yhxA and yodT;</li> <li>Haemophilus influenzae diaminobutyrate--2-oxoglutarate aminotransferase (HI0949) [[cite:PUB00017555]];</li> <li>Caenorhabditis elegans alanine--glyoxylate aminotransferase 2-like (T01B11.2).</li></ul>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Associated Lotus transcripts 42

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: