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IPR010435

Description

IPR010435 is a C5a peptidase/Subtilisin-like protease SBT2-like, Fn3-like domain.

<p>This is a Fn3-like domain found as the first of three on streptococcal C5a peptidase (SCP), a subtilisin-like, highly specific protease and adhesin/invasin that acts as an essential GAS virulence factor for the rapid dissemination of bacteria in soft tissues [[cite:PUB00046871], [cite:PUB00154368], [cite:PUB00154367]]. This domain is also found at the C-terminal of subtilisin-like protease SBT2 from Arabidopsis and in PI-II-type proteinase.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Cellular component Cell wall The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
Cellular component Membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR10795:SF431 PANTHER 1 50.00