Description

IPR011162 is a MHC classes I/II-like antigen recognition protein.

<p>Major Histocompatibility Complex (MHC) glycoproteins are heterodimeric cell surface receptors that function to present antigen peptide fragments to T cells responsible for cell-mediated immune responses. MHC molecules can be subdivided into two groups on the basis of structure and function: class I molecules present intracellular antigen peptide fragments (~10 amino acids) on the surface of the host cells to cytotoxic T cells; class II molecules present exogenously derived antigenic peptides (~15 amino acids) to helper T cells. MHC class I and II molecules are assembled and loaded with their peptide ligands via different mechanisms. However, both present peptide fragments rather than entire proteins to T cells, and are required to mount an immune response.</p> <p>This superfamily represents MHC class I and II-like antigen-recognition domains from:</p> <ul> <li>MHC class II, N-terminal domains of alpha and beta chains [[cite:PUB00025626]]</li> <li>MHC class I, alpha-1 and alpha-2 domains [[cite:PUB00035588]]</li> <li>MHC class I related proteins, such as gammadelta T-cell ligand [[cite:PUB00035589]], Ulbp3 [[cite:PUB00035590]], Fc (IgG) receptor (alpha-1 and -2 domains) [[cite:PUB00025007]], CD1 (alpha-1 and -2 domains) [[cite:PUB00035591]], zinc-alpha-2-glycoprotein ZAG (fat depleting factor) [[cite:PUB00035592]]</li> <li>Immunomodulatory protein m144, alpha-1 and alpha-2 domains [[cite:PUB00035593]]</li> <li>Haemochromatosis protein Hfe, alpha-1 and alpha-2 domains [[cite:PUB00035594]]</li> <li>NK cell ligand RAE-1 beta [[cite:PUB00035595]]</li> <li>Endothelial protein C receptor (phospholipid-binding protein) [[cite:PUB00035596]]</li> </ul>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 5

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: