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IPR011183 is a Pyrophosphate-dependent phosphofructokinase PfpB.
<p>Diphosphate--fructose-6-phosphate 1-phosphotransferase catalyses the addition of phosphate from diphosphate (PPi) to fructose 6-phosphate to give fructose 1,6-bisphosphate ([ec:2.7.1.90]). The enzyme is also known as pyrophosphate-dependent phosphofructokinase. The usage of PPi-dependent enzymes in glycolysis presumably frees up ATP for other processes [[cite:PUB00014390]]. [interpro:IPR012828] represents the ATP-dependent 6-phosphofructokinase enzyme contained within Phosphofructokinase. This entry contains primarily bacterial, plant alpha, and plant beta sequences. These may be dimeric nonallosteric enzymes (bacteria) or allosteric heterotetramers (plants) [[cite:PUB00014411]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | ATP binding | Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | ||
| Biological process | Glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. | ||
| Molecular function | Diphosphate-fructose-6-phosphate 1-phosphotransferase activity | Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha-like isoform X1 [Cicer arietinum] gi|502123626|ref|XP_004498195.1| | 10 | ||
| – | PREDICTED: pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha-like isoform X1 [Cicer arietinum] gi|502123626|ref|XP_004498195.1| | 14 | ||
| – | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase subunit beta [Medicago truncatula] gi|357480393|ref|XP_003610482.1| | 14 | ||
| – | PREDICTED: pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta-like [Glycine max] gi|356532285|ref|XP_003534704.1| | 14 | ||
| – | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha; TAIR: AT1G76550.1 Phosphofructokinase family protein; Swiss-Prot: sp|Q41140|PFPA_RICCO Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha; TrEMBL-Plants: tr|A0A0L9UUG2|A0A0L9UUG2_PHAAN Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit alpha; Found in the gene: LotjaGi2g1v0011400 | 13 | ||
| – | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TAIR: AT1G12000.1 Phosphofructokinase family protein; Swiss-Prot: sp|Q41141|PFPB_RICCO Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TrEMBL-Plants: tr|A0A151SU15|A0A151SU15_CAJCA Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; Found in the gene: LotjaGi4g1v0010600 | 15 | ||
| – | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TAIR: AT1G12000.1 Phosphofructokinase family protein; Swiss-Prot: sp|Q41141|PFPB_RICCO Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TrEMBL-Plants: tr|A0A151SU15|A0A151SU15_CAJCA Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; Found in the gene: LotjaGi4g1v0010600 | 15 | ||
| – | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TAIR: AT1G12000.1 Phosphofructokinase family protein; Swiss-Prot: sp|Q41141|PFPB_RICCO Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TrEMBL-Plants: tr|A0A151SU15|A0A151SU15_CAJCA Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; Found in the gene: LotjaGi4g1v0010600 | 15 | ||
| – | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TAIR: AT1G12000.1 Phosphofructokinase family protein; Swiss-Prot: sp|Q41141|PFPB_RICCO Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TrEMBL-Plants: tr|I1KZW7|I1KZW7_SOYBN Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; Found in the gene: LotjaGi6g1v0289400 | 15 | ||
| – | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TAIR: AT1G12000.1 Phosphofructokinase family protein; Swiss-Prot: sp|Q41141|PFPB_RICCO Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TrEMBL-Plants: tr|I1KZW7|I1KZW7_SOYBN Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; Found in the gene: LotjaGi6g1v0289400 | 15 | ||
| – | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; TAIR: AT1G12000.1 Phosphofructokinase family protein; Swiss-Prot: sp|Q8W4M5|PFPB1_ARATH Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta 1; TrEMBL-Plants: tr|I1KZW7|I1KZW7_SOYBN Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta; Found in the gene: LotjaGi6g1v0289400 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR02477 | TIGRFAM | 1 | 9.09 |