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IPR011387 is a Translation initiation factor 2A.
<p>Eukaryotic initiation factor 2A (eIF2A) directly binds the initiator methionyl-tRNA (Met-tRNA(i)) to 40 S ribosomal subunits in a codon-dependent manner [[cite:PUB00085136]]. It may act by impiging the expression of specific proteins [[cite:PUB00014619]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. | ||
| Biological process | Translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Eukaryotic translation initiation factor; TAIR: AT1G73180.1 Eukaryotic translation initiation factor eIF2A family protein; Swiss-Prot: sp|O74965|EIF2A_SCHPO Eukaryotic translation initiation factor 2A; TrEMBL-Plants: tr|A0A1J7G1L6|A0A1J7G1L6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0485900 | 7 | ||
| – | Eukaryotic translation initiation factor 3 subunit B; TAIR: AT1G73180.1 Eukaryotic translation initiation factor eIF2A family protein; Swiss-Prot: sp|Q54PV7|EIF2A_DICDI Eukaryotic translation initiation factor 2A; TrEMBL-Plants: tr|I3SWY0|I3SWY0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0109800_LC | 7 | ||
| – | Eukaryotic translation initiation factor 3 subunit, putative; TAIR: AT1G73180.1 Eukaryotic translation initiation factor eIF2A family protein; Swiss-Prot: sp|Q54PV7|EIF2A_DICDI Eukaryotic translation initiation factor 2A; TrEMBL-Plants: tr|I3SWY0|I3SWY0_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0109800_LC | 5 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |