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IPR011858

Source: InterPro

Description

IPR011858 is a His6-like, eukaryotic-type.

<p>This enzyme acts in the biosynthesis of histidine and has been characterised in Saccharomyces cerevisiae [[cite:PUB00001877]] and Arabidopsis [[cite:PUB00015487]] where it complements the Escherichia coli HisA gene. In eukaryotes the gene is known as His6. In bacteria, this gene is found in Fibrobacter succinogenes(Bacteroides succinogenes), presumably due to lateral gene transfer from plants in the rumen gut.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000105
Biological process Histidine biosynthetic process The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
Subterm of
GO:0003949
Molecular function 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
Subterm of

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj1g3v0969950.1
– PREDICTED: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] gi|502078164|ref|XP_004485858.1|
Domains
10
Lj1g3v0969950.2
– PREDICTED: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] gi|356548431|ref|XP_003542605.1|
Domains
11
LotjaGi1g1v0283900.1
– 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TAIR: AT2G36230.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|O82782|HIS3_ARATH 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, chloroplastic; TrEMBL-Plants: tr|K7LZZ8|K7LZZ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0283900
Domains
11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd04723 CDD 1 33.33