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IPR012392

Source: InterPro

Description

IPR012392 is a Very-long-chain 3-ketoacyl-CoA synthase.

<p>This group represents 3-ketoacyl-CoA synthases (KCSs) from plants [[cite:PUB00015963], [cite:PUB00073456]]. They are also known as very long-chain fatty acid (VLCFA) condensing enzymes, and they catalyse the first committed step during the fatty acid elongation process, which is the condensation of C2 units to acyl-CoA. Arabidopsis contains 21 KCS members [[cite:PUB00073455]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006633
Biological process Fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
Subterm of
GO:0016020
Cellular component Membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
Subterm of
GO:0016747
Molecular function Transferase activity, transferring acyl groups other than amino-acyl groups Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
Subterm of

Associated Lotus transcripts 56

Transcript Name Description Predicted domains Domain count
Lj0g3v0065089.1
– PREDICTED: 3-ketoacyl-CoA synthase 11-like [Glycine max] gi|356535335|ref|XP_003536202.1|
Domains
16
Lj0g3v0078429.1
– PREDICTED: 3-ketoacyl-CoA synthase 7-like [Glycine max] gi|356557495|ref|XP_003547051.1|
Domains
11
Lj0g3v0216389.1
– 3-ketoacyl-CoA synthase [Medicago truncatula] gi|357472603|ref|XP_003606586.1|
Domains
16
Lj0g3v0220359.1
– PREDICTED: 3-ketoacyl-CoA synthase 12-like [Glycine max] gi|356550239|ref|XP_003543495.1|
Domains
15
Lj0g3v0241719.1
– PREDICTED: 3-ketoacyl-CoA synthase 5-like [Glycine max] gi|356574442|ref|XP_003555356.1|
Domains
15
Lj0g3v0246159.1
– PREDICTED: 3-ketoacyl-CoA synthase 4-like [Cicer arietinum] gi|502149248|ref|XP_004507452.1|
Domains
13
Lj0g3v0324009.1
– PREDICTED: 3-ketoacyl-CoA synthase 4-like [Vitis vinifera] gi|359475340|ref|XP_003631663.1|
Domains
16
Lj1g3v1798580.1
– PREDICTED: 3-ketoacyl-CoA synthase 10-like [Glycine max] gi|356507127|ref|XP_003522322.1|
Domains
14
Lj1g3v1798600.1
– Beta-ketoacyl-CoA synthase [Arabidopsis thaliana] gi|62318951|dbj|BAD94049.1|
Domains
8
Lj1g3v1914960.1
– Beta-ketoacyl-coa synthase family protein [Populus trichocarpa] gi|224089128|ref|XP_002308642.1|
Domains
16
Lj1g3v4667830.1
– PREDICTED: 3-ketoacyl-CoA synthase 5-like [Glycine max] gi|356574442|ref|XP_003555356.1|
Domains
16
Lj1g3v5060470.1
– 3-ketoacyl-CoA synthase [Medicago truncatula] gi|357512625|ref|XP_003626601.1|
Domains
16
Lj2g3v0856560.1
– PREDICTED: 3-ketoacyl-CoA synthase 10-like [Glycine max] gi|356507127|ref|XP_003522322.1|
Domains
14
Lj2g3v1154110.1
– 3-ketoacyl-CoA synthase [Arachis hypogaea] gi|269854053|gb|ACZ51240.1|
Domains
16
Lj2g3v1199860.1
– Fatty acid elongase 3-ketoacyl-CoA synthase [Medicago truncatula] gi|357497433|ref|XP_003619005.1|
Domains
7
Lj3g3v0170760.1
–
Domains
16
Lj3g3v0170770.1
– PREDICTED: 3-ketoacyl-CoA synthase 4-like [Cicer arietinum] gi|502149248|ref|XP_004507452.1|
Domains
16
Lj3g3v3363310.1
– CM0216.300.nc [Lotus japonicus] gi|164564732|dbj|BAF98214.1|
Domains
16
Lj4g3v1812470.1
– PREDICTED: 3-ketoacyl-CoA synthase 11-like [Glycine max] gi|356511628|ref|XP_003524525.1|
Domains
16
Lj5g3v0106070.1
– PREDICTED: 3-ketoacyl-CoA synthase 4-like [Glycine max] gi|356562355|ref|XP_003549437.1|
Domains
16
Lj5g3v1207760.1
– PREDICTED: 3-ketoacyl-CoA synthase 11-like [Glycine max] gi|356535335|ref|XP_003536202.1|
Domains
10
Lj5g3v1207770.1
– PREDICTED: 3-ketoacyl-CoA synthase 11-like [Cicer arietinum] gi|502116381|ref|XP_004495403.1|
Domains
7
Lj5g3v1207790.1
– PREDICTED: 3-ketoacyl-CoA synthase 11-like [Glycine max] gi|356574783|ref|XP_003555524.1|
Domains
11
Lj5g3v2203980.1
– 3-ketoacyl-CoA synthase [Arachis hypogaea] gi|269854053|gb|ACZ51240.1|
Domains
16
Lj5g3v2288650.1
– PREDICTED: 3-ketoacyl-CoA synthase 21-like [Cicer arietinum] gi|502121440|ref|XP_004497320.1|
Domains
17
Lj5g3v2288650.2
– PREDICTED: 3-ketoacyl-CoA synthase 21-like [Cicer arietinum] gi|502121440|ref|XP_004497320.1|
Domains
17
Lj5g3v2288660.1
– PREDICTED: 3-ketoacyl-CoA synthase 21-like [Glycine max] gi|356536510|ref|XP_003536780.1|
Domains
10
Lj6g3v0000160.1
– PREDICTED: 3-ketoacyl-CoA synthase 11-like [Cicer arietinum] gi|502116381|ref|XP_004495403.1|
Domains
7
Lj6g3v1464000.1
– PREDICTED: probable 3-ketoacyl-CoA synthase 20-like [Glycine max] gi|356558171|ref|XP_003547381.1|
Domains
14
Lj6g3v2019780.1
– PREDICTED: 3-ketoacyl-CoA synthase 10-like [Cicer arietinum] gi|502077924|ref|XP_004485786.1|
Domains
13
LotjaGi1g1v0373200.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G26250.1 3-ketoacyl-CoA synthase 10; Swiss-Prot: sp|Q570B4|KCS10_ARATH 3-ketoacyl-CoA synthase 10; TrEMBL-Plants: tr|A0A1J7H3X6|A0A1J7H3X6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0373200
Domains
16
LotjaGi1g1v0373200.2
– 3-ketoacyl-CoA synthase; TAIR: AT2G26250.1 3-ketoacyl-CoA synthase 10; Swiss-Prot: sp|Q570B4|KCS10_ARATH 3-ketoacyl-CoA synthase 10; TrEMBL-Plants: tr|A0A1J7H3X6|A0A1J7H3X6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0373200
Domains
16
LotjaGi1g1v0373200.3
– 3-ketoacyl-CoA synthase; TAIR: AT2G26250.1 3-ketoacyl-CoA synthase 10; Swiss-Prot: sp|Q570B4|KCS10_ARATH 3-ketoacyl-CoA synthase 10; TrEMBL-Plants: tr|A0A1J7H3X6|A0A1J7H3X6_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0373200
Domains
16
LotjaGi1g1v0387500.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|B9H9R8|B9H9R8_POPTR 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi1g1v0387500
Domains
16
LotjaGi1g1v0437300.1
– 3-ketoacyl-CoA synthase; TAIR: AT1G19440.1 3-ketoacyl-CoA synthase 4; Swiss-Prot: sp|Q9LN49|KCS4_ARATH 3-ketoacyl-CoA synthase 4; TrEMBL-Plants: tr|M5VMR3|M5VMR3_PRUPE 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi1g1v0437300
Domains
15
LotjaGi1g1v0796000.1
– 3-ketoacyl-CoA synthase; TAIR: AT1G01120.1 3-ketoacyl-CoA synthase 1; Swiss-Prot: sp|Q9MAM3|KCS1_ARATH 3-ketoacyl-CoA synthase 1; TrEMBL-Plants: tr|Q2HTC9|Q2HTC9_MEDTR 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi1g1v0796000
Domains
16
LotjaGi2g1v0100000.1
– 3-ketoacyl-CoA synthase; TAIR: AT1G04220.1 3-ketoacyl-CoA synthase 2; Swiss-Prot: sp|Q5XEP9|KCS2_ARATH 3-ketoacyl-CoA synthase 2; TrEMBL-Plants: tr|I1K220|I1K220_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi2g1v0100000
Domains
17
LotjaGi2g1v0276500.1
– 3-ketoacyl-CoA synthase; TAIR: AT1G68530.1 3-ketoacyl-CoA synthase 6; Swiss-Prot: sp|Q9XF43|KCS6_ARATH 3-ketoacyl-CoA synthase 6; TrEMBL-Plants: tr|A0A151RPM4|A0A151RPM4_CAJCA 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi2g1v0276500
Domains
16
LotjaGi2g1v0367500.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G28630.1 3-ketoacyl-CoA synthase 12; Swiss-Prot: sp|Q9SIB2|KCS12_ARATH 3-ketoacyl-CoA synthase 12; TrEMBL-Plants: tr|G7JSN8|G7JSN8_MEDTR 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi2g1v0367500
Domains
15
LotjaGi3g1v0278600.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G28630.1 3-ketoacyl-CoA synthase 12; Swiss-Prot: sp|Q9SIB2|KCS12_ARATH 3-ketoacyl-CoA synthase 12; TrEMBL-Plants: tr|A0A151SUW9|A0A151SUW9_CAJCA 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi3g1v0278600
Domains
14
LotjaGi3g1v0508600.1
– 3-ketoacyl-CoA synthase; TAIR: AT1G19440.1 3-ketoacyl-CoA synthase 4; Swiss-Prot: sp|Q9LN49|KCS4_ARATH 3-ketoacyl-CoA synthase 4; TrEMBL-Plants: tr|G7JHB4|G7JHB4_MEDTR 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi3g1v0508600
Domains
16
LotjaGi3g1v0510500.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|B0BLH8|B0BLH8_LOTJA 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi3g1v0510500
Domains
16
LotjaGi3g1v0510500.2
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|B0BLH8|B0BLH8_LOTJA 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi3g1v0510500
Domains
16
LotjaGi4g1v0266000.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|I1K1C8|I1K1C8_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi4g1v0266000
Domains
16
LotjaGi4g1v0266000.2
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|I1K1C8|I1K1C8_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi4g1v0266000
Domains
16
LotjaGi4g1v0266000.3
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|I1K1C8|I1K1C8_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi4g1v0266000
Domains
16
LotjaGi5g1v0193100.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|I1LC39|I1LC39_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi5g1v0193100
Domains
17
LotjaGi5g1v0193100.2
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|I1LC39|I1LC39_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi5g1v0193100
Domains
17
LotjaGi5g1v0193100.3
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|I1LC39|I1LC39_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi5g1v0193100
Domains
17
LotjaGi5g1v0193100.4
– 3-ketoacyl-CoA synthase; TAIR: AT1G04220.1 3-ketoacyl-CoA synthase 2; Swiss-Prot: sp|Q5XEP9|KCS2_ARATH 3-ketoacyl-CoA synthase 2; TrEMBL-Plants: tr|I1LC39|I1LC39_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi5g1v0193100
Domains
11
LotjaGi5g1v0307800.1
– 3-ketoacyl-CoA synthase; TAIR: AT1G68530.1 3-ketoacyl-CoA synthase 6; Swiss-Prot: sp|Q9XF43|KCS6_ARATH 3-ketoacyl-CoA synthase 6; TrEMBL-Plants: tr|K7LL62|K7LL62_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi5g1v0307800
Domains
16
LotjaGi5g1v0340300.1
– 3-ketoacyl-CoA synthase; TAIR: AT1G68530.1 3-ketoacyl-CoA synthase 6; Swiss-Prot: sp|Q9XF43|KCS6_ARATH 3-ketoacyl-CoA synthase 6; TrEMBL-Plants: tr|I1E3D2|I1E3D2_ARAHY 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi5g1v0340300
Domains
16
LotjaGi5g1v0358700.1
– 3-ketoacyl-CoA synthase; TAIR: AT5G04530.1 3-ketoacyl-CoA synthase 19; Swiss-Prot: sp|Q9LZ72|KCS19_ARATH 3-ketoacyl-CoA synthase 19; TrEMBL-Plants: tr|A0A072VS55|A0A072VS55_MEDTR 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi5g1v0358700
Domains
16
LotjaGi6g1v0001200.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G26640.1 3-ketoacyl-CoA synthase 11; Swiss-Prot: sp|O48780|KCS11_ARATH 3-ketoacyl-CoA synthase 11; TrEMBL-Plants: tr|I1LC39|I1LC39_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi6g1v0001200
Domains
16
LotjaGi6g1v0250900.1
– 3-ketoacyl-CoA synthase; TAIR: AT5G49070.1 3-ketoacyl-CoA synthase 21; Swiss-Prot: sp|Q9FH27|KCS21_ARATH Probable 3-ketoacyl-CoA synthase 21; TrEMBL-Plants: tr|A0A151T5W8|A0A151T5W8_CAJCA 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi6g1v0250900
Domains
10
LotjaGi6g1v0331200.1
– 3-ketoacyl-CoA synthase; TAIR: AT2G26250.1 3-ketoacyl-CoA synthase 10; Swiss-Prot: sp|Q570B4|KCS10_ARATH 3-ketoacyl-CoA synthase 10; TrEMBL-Plants: tr|I1MEJ6|I1MEJ6_SOYBN 3-ketoacyl-CoA synthase; Found in the gene: LotjaGi6g1v0331200
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00831 CDD 1 1.79