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IPR012622

Source: InterPro

Description

IPR012622 is a Potassium channel toxin gamma/Ergtoxin.

<p>The Ergtoxin (ErgTx) family is a class of peptides from scorpion venom that specifically block ERG (ether-a-go-go-related gene) K+ channels of the nerve, heart and endocrine cells [[cite:PUB00033819], [cite:PUB00029028], [cite:PUB00033820]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005576
Cellular component Extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
Subterm of
GO:0009405
Biological process Pathogenesis The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
Subterm of
GO:0019870
Molecular function Potassium channel inhibitor activity Stops, prevents, or reduces the activity of a potassium channel.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi2g1v0337100.1
– Alpha/beta-Hydrolases superfamily protein; TAIR: AT1G32190.1 alpha/beta-Hydrolases superfamily protein; Swiss-Prot: sp|Q7ZVZ7|AB17C_DANRE Protein ABHD17C; TrEMBL-Plants: tr|A0A0L9URM7|A0A0L9URM7_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0337100
Domains
9

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF53474 SUPERFAMILY 1 100.00