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IPR012936 is a Endoplasmic reticulum vesicle transporter, C-terminal.
<p>This entry represents the C-terminal domain of the endoplasmic reticulum vesicle transporter proteins.</p> <p>Proteins included in this entry are conserved from plants and fungi to humans. Erv46 (ERGIC3) works in close conjunction with Erv41 (ERGIC2) and together they form a complex which cycles between the endoplasmic reticulum and Golgi complex. Erv46-41 interacts strongly with the endoplasmic reticulum glucosidase II. Mammalian glucosidase II comprises a catalytic alpha-subunit and a 58kDa beta subunit, which is required for ER localisation. All proteins identified biochemically as Erv41p-Erv46p interactors are localised to the early secretory pathway and are involved in protein maturation and processing in the ER and/or sorting into COPII vesicles for transport to the Golgi [[cite:PUB00063190]].</p> <p>Proteins containing this domain also include disulfide isomerase (PDI)-C subfamily members from Arabidopsis. They are chimeric proteins containing the thioredoxin (Trx) domain of PDIs, and the conserved N- and C-terminal domains of Erv cargo receptors [[cite:PUB00089776]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: endoplasmic reticulum-Golgi intermediate compartment protein 3-like [Glycine max] gi|356575088|ref|XP_003555674.1| | 10 | ||
| – | PREDICTED: protein disulfide-isomerase 5-4-like [Glycine max] gi|356517290|ref|XP_003527321.1| | 17 | ||
| – | PREDICTED: endoplasmic reticulum-Golgi intermediate compartment protein 3-like [Glycine max] gi|356512071|ref|XP_003524744.1| | 9 | ||
| – | PREDICTED: endoplasmic reticulum-Golgi intermediate compartment protein 3-like [Cicer arietinum] gi|502142075|ref|XP_004504780.1| | 4 | ||
| – | Endoplasmic reticulum-Golgi intermediate compartment protein 3; TAIR: AT1G36050.2 Endoplasmic reticulum vesicle transporter protein; Swiss-Prot: sp|Q803I2|ERGI3_DANRE Endoplasmic reticulum-Golgi intermediate compartment protein 3; TrEMBL-Plants: tr|G7KA80|G7KA80_MEDTR Endoplasmic reticulum vesicle transporter; Found in the gene: LotjaGi1g1v0147300 | 10 | ||
| – | Endoplasmic reticulum-Golgi intermediate compartment protein 3; TAIR: AT1G36050.2 Endoplasmic reticulum vesicle transporter protein; Swiss-Prot: sp|Q803I2|ERGI3_DANRE Endoplasmic reticulum-Golgi intermediate compartment protein 3; TrEMBL-Plants: tr|G7KA80|G7KA80_MEDTR Endoplasmic reticulum vesicle transporter; Found in the gene: LotjaGi1g1v0147300 | 10 | ||
| – | Protein disulfide isomerase; TAIR: AT4G27080.1 PDI-like 5-4; Swiss-Prot: sp|Q9T042|PDI54_ARATH Protein disulfide-isomerase 5-4; TrEMBL-Plants: tr|A0A0B2SSL7|A0A0B2SSL7_GLYSO Protein disulfide-isomerase 5-4; Found in the gene: LotjaGi3g1v0149200 | 18 | ||
| – | Protein disulfide isomerase; TAIR: AT4G27080.1 PDI-like 5-4; Swiss-Prot: sp|Q9T042|PDI54_ARATH Protein disulfide-isomerase 5-4; TrEMBL-Plants: tr|A0A0B2SSL7|A0A0B2SSL7_GLYSO Protein disulfide-isomerase 5-4; Found in the gene: LotjaGi3g1v0149200 | 18 | ||
| – | Protein disulfide-isomerase 5-4; TAIR: AT4G27080.1 PDI-like 5-4; Swiss-Prot: sp|Q9T042|PDI54_ARATH Protein disulfide-isomerase 5-4; TrEMBL-Plants: tr|I1LUQ2|I1LUQ2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0237800 | 17 | ||
| – | Endoplasmic reticulum-Golgi intermediate compartment protein 3; TAIR: AT1G36050.2 Endoplasmic reticulum vesicle transporter protein; Swiss-Prot: sp|Q66KH2|ERGI3_XENLA Endoplasmic reticulum-Golgi intermediate compartment protein 3; TrEMBL-Plants: tr|K7KPQ8|K7KPQ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0033900 | 10 | ||
| – | Endoplasmic reticulum-Golgi intermediate compartment protein 3; TAIR: AT3G22290.1 Endoplasmic reticulum vesicle transporter protein; Swiss-Prot: sp|Q803I2|ERGI3_DANRE Endoplasmic reticulum-Golgi intermediate compartment protein 3; TrEMBL-Plants: tr|A0A072UZF4|A0A072UZF4_MEDTR Endoplasmic reticulum vesicle transporter; Found in the gene: LotjaGi6g1v0029500 | 11 | ||
| – | Endoplasmic reticulum-Golgi intermediate compartment protein 3; TAIR: AT3G22290.1 Endoplasmic reticulum vesicle transporter protein; Swiss-Prot: sp|Q803I2|ERGI3_DANRE Endoplasmic reticulum-Golgi intermediate compartment protein 3; TrEMBL-Plants: tr|A0A072UZF4|A0A072UZF4_MEDTR Endoplasmic reticulum vesicle transporter; Found in the gene: LotjaGi6g1v0029500 | 11 | ||
| – | Endoplasmic reticulum-Golgi intermediate compartment protein 3; TAIR: AT3G22290.1 Endoplasmic reticulum vesicle transporter protein; Swiss-Prot: sp|Q803I2|ERGI3_DANRE Endoplasmic reticulum-Golgi intermediate compartment protein 3; TrEMBL-Plants: tr|A0A072UZF4|A0A072UZF4_MEDTR Endoplasmic reticulum vesicle transporter; Found in the gene: LotjaGi6g1v0029500 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 7.69 |