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IPR013986 is a DExx box DNA helicase domain superfamily.
<p>This domain superfamily is found in DExx type DNA helicases, such as the hexameric essential helicases PcrA from Gram-positive bacteria and Rep and UvrD from Gram-negative bacteria [[cite:PUB00035958]]. PcrA is essential for cell growth in Bacillus species, as it is required for rolling circle replication, unwinding DNA using an active inchworm mechanism [[cite:PUB00035955]]. UvrD from Escherichia coli is a superfamily 1 (SF1) helicase involved in several DNA metabolic processes, including recombination and repair [[cite:PUB00035956]], while Rep affects the rate of replication fork progression in E. coli and is required for the replication of certain phages [[cite:PUB00035957]]. The domain is also found in the exodeoxyribonuclease V gamma chain, which has a wide variety of catalytic activities including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase activities.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | ATP-dependent DNA helicase; TAIR: AT4G25120.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|D1KF50|SRS2L_ARATH ATP-dependent DNA helicase SRS2-like protein At4g25120; TrEMBL-Plants: tr|I1NHX8|I1NHX8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi5g1v0161400 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |