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IPR014362 is a Glutamate dehydrogenase.
<p>This entry represents glutamate dehydrogenases (GDH). The tertiary structure have been solved for the GDHs from Thermotoga maritima and Pyrococcus furiosus, both of which are thermostable because of an ion-pair network in the hinge region [[cite:PUB00023488]]. Some GDHs are NADP-specific, such as GdhA from Escherichia coli, which catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia [[cite:PUB00082609], [cite:PUB00082610]]. In eukaryotes, NADP-dependent GDHs may be mitochondrial, such as GluD from Dictyostelium discoideum [[cite:PUB00082611]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: glutamate dehydrogenase 1-like isoform X1 [Cicer arietinum] gi|502107100|ref|XP_004493157.1| | 20 | ||
| – | PREDICTED: glutamate dehydrogenase 2-like [Glycine max] gi|356497088|ref|XP_003517396.1| | 20 | ||
| – | PREDICTED: NADP-specific glutamate dehydrogenase-like [Glycine max] gi|356526047|ref|XP_003531631.1| | 17 | ||
| – | PREDICTED: glutamate dehydrogenase 2-like [Glycine max] gi|356497088|ref|XP_003517396.1| | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|C6TDZ0|C6TDZ0_SOYBN Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|V7CUX4|V7CUX4_PHAVU Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|A0A142F3D2|A0A142F3D2_ARAHY Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|A0A142F3D2|A0A142F3D2_ARAHY Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|A0A142F3D2|A0A142F3D2_ARAHY Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|C6TDZ0|C6TDZ0_SOYBN Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|A0A151T9S6|A0A151T9S6_CAJCA Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|A0A151T9S6|A0A151T9S6_CAJCA Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|V7CUX4|V7CUX4_PHAVU Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G18170.1 glutamate dehydrogenase 1; Swiss-Prot: sp|Q43314|DHE1_ARATH Glutamate dehydrogenase 1; TrEMBL-Plants: tr|V7CUX4|V7CUX4_PHAVU Glutamate dehydrogenase; Found in the gene: LotjaGi1g1v0642800 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G07440.1 glutamate dehydrogenase 2; Swiss-Prot: sp|Q38946|DHE2_ARATH Glutamate dehydrogenase 2; TrEMBL-Plants: tr|I1J9Q7|I1J9Q7_SOYBN Glutamate dehydrogenase; Found in the gene: LotjaGi2g1v0419000 | 20 | ||
| – | Glutamate dehydrogenase; TAIR: AT5G07440.1 glutamate dehydrogenase 2; Swiss-Prot: sp|Q38946|DHE2_ARATH Glutamate dehydrogenase 2; TrEMBL-Plants: tr|I1J9Q7|I1J9Q7_SOYBN Glutamate dehydrogenase; Found in the gene: LotjaGi4g1v0195400 | 20 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd01076 | CDD | 1 | 6.25 |