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IPR017182

Description

IPR017182 is a Methyltransferase METTL16/PsiM.

<p>METTL16 is an U6 snRNA methyltransferase that methylates adenosine residues of a subset of RNAs. It plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts [[cite:PUB00086421]].</p> <p>This entry also includes PsiM from Psilocybe cubensis. PsiM is part of the gene cluster that mediates the biosynthesis of psilocybin, a psychotropic tryptamine-derived natural product. It serves as a methyltransferase that catalyze iterative N-methyl transfer as the terminal biosynthetic step [[cite:PUB00086873]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
PREDICTED: methyltransferase-like protein 16 homolog [Cicer arietinum] gi|502141838|ref|XP_004504663.1| 10
Methyltransferase-like protein; TAIR: AT2G21070.3 methyltransferase; Swiss-Prot: sp|Q6DC64|MET16_DANRE Methyltransferase-like protein 16; TrEMBL-Plants: tr|A0A0B2R5N2|A0A0B2R5N2_GLYSO Methyltransferase-like protein; Found in the gene: LotjaGi4g1v0020500 8

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00