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IPR017408

Source: InterPro

Description

IPR017408 is a Arginine N-methyltransferase 2.

<p>Arginine N-methyltransferase 2 is a delta-N-monomethylarginine transferase which monomethylates 'Arg-67' of ribosomal protein L12 [[cite:PUB00058143]].</p> <p>Protein arginine methyltransferases (PRMT) have been implicated in the regulation of transcription. They are recruited to promoters via their interaction with transcription factors and exert their co-activator function by methylating arginine residues in histones and other chromatin proteins [[cite:PUB00043525]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0016274
Molecular function Protein-arginine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi1g1v0360600.1
– Ankyrin repeat family protein; TAIR: AT5G65860.2 ankyrin repeat family protein; Swiss-Prot: sp|P0CQ69|RMT2_CRYNB Protein arginine N-methyltransferase 2; TrEMBL-Plants: tr|A0A1J7HQ34|A0A1J7HQ34_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0360600
Domains
18

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd02440 CDD 1 100.00