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IPR019010 is a Eukaryotic translation initiation factor 3 subunit E, N-terminal.
<p>This entry represents the N-terminal domain of the eukaryotic translation initiation factor 3 subunit E. EIF3 is required in protein synthesis in mammalian cells and, together with other initiation factors, stimulates binding of initiator methionyl-tRNAi and mRNA to the 40S ribosomal subunit to form the 48 S initiation complex [[cite:PUB00045290]]. The eIF3 complex also prevents premature association of the 40 and 60 S ribosomal subunits and interacts with other initiation factors involved in start codon selection. EIF3 has at least 13 protein components (eIF3a-m or 1-13), where subunits h, i, k, and m are likely to be on the periphery of the complex [[cite:PUB00045290]]. Subunit 6 is produced by the int6 gene, one of the frequent integration sites for mouse mammary tumor viruses [[cite:PUB00045291]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: eukaryotic translation initiation factor 3 subunit E-like [Glycine max] gi|356500541|ref|XP_003519090.1| | 17 | ||
| – | Eukaryotic translation initiation factor 3 subunit E; TAIR: AT3G57290.1 eukaryotic translation initiation factor 3E; Swiss-Prot: sp|Q9C5Z3|EIF3E_ARATH Eukaryotic translation initiation factor 3 subunit E; TrEMBL-Plants: tr|V7BI41|V7BI41_PHAVU Eukaryotic translation initiation factor 3 subunit E; Found in the gene: LotjaGi5g1v0135400 | 17 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF46785 | SUPERFAMILY | 1 | 50.00 |