Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR019770 is a Eukaryotic translation initiation factor 4E (eIF-4E), conserved site.
<p>Eukaryotic translation initiation factor 4E (eIF-4E) [[cite:PUB00000866]] is a protein that binds to the cap structure of eukaryotic cellular mRNAs. eIF-4E recognises and binds the 7-methylguanosine-containing (m7Gppp) cap during an early step in the initiation of protein synthesis and facilitates ribosome binding to a mRNA by inducing the unwinding of its secondary structures.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | RNA binding | Interacting selectively and non-covalently with an RNA molecule or a portion thereof. | ||
| Molecular function | Translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. | ||
| Cellular component | Cytoplasm | All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. | ||
| Biological process | Translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|Q9FK59|IF4E5_ARATH Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|C6SW38|C6SW38_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 10 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|A3RCV9|IF4E3_WHEAT Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|I1JD60|I1JD60_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|A3RCV9|IF4E3_WHEAT Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|I1JD60|I1JD60_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|A3RCV9|IF4E3_WHEAT Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|I1JD60|I1JD60_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G35620.1 Eukaryotic initiation factor 4E protein; Swiss-Prot: sp|Q03389|IF4E2_WHEAT Eukaryotic translation initiation factor isoform 4E-2; TrEMBL-Plants: tr|I3T1M7|I3T1M7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0008200 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT4G18040.1 eukaryotic translation initiation factor 4E; Swiss-Prot: sp|O23252|IF4E1_ARATH Eukaryotic translation initiation factor 4E-1; TrEMBL-Plants: tr|K0P2S0|K0P2S0_ARAHY Eukaryotic translation initiation factor 4E; Found in the gene: LotjaGi6g1v0314500 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |