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IPR023398 is a Translation Initiation factor eIF- 4e-like.
<p>Eukaryotic translation initiation factor 4E (eIF-4E) [[cite:PUB00000866]] is a protein that binds to the cap structure of eukaryotic cellular mRNAs. eIF-4E recognises and binds the 7-methylguanosine-containing (m7Gppp) cap during an early step in the initiation of protein synthesis and facilitates ribosome binding to a mRNA by inducing the unwinding of its secondary structures. A tryptophan in the central part of the sequence of human eIF-4E seems to be implicated in cap-binding [[cite:PUB00001603]].</p> <p>This entry includes a group of eIF4E-like protein. These proteins consist of a curved eight-stranded antiparallel β-sheet, decorated with three helices on the convex face and three smaller helices inserted in connecting loops [[cite:PUB00036324]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: eukaryotic translation initiation factor 4E type 3-like [Glycine max] gi|356498848|ref|XP_003518260.1| | 8 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|Q9FK59|IF4E5_ARATH Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|C6SW38|C6SW38_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 10 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|A3RCV9|IF4E3_WHEAT Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|I1JD60|I1JD60_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|A3RCV9|IF4E3_WHEAT Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|I1JD60|I1JD60_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G18110.1 Putative cap-binding protein; Swiss-Prot: sp|A3RCV9|IF4E3_WHEAT Eukaryotic translation initiation factor NCBP; TrEMBL-Plants: tr|I1JD60|I1JD60_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0109300 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT5G35620.1 Eukaryotic initiation factor 4E protein; Swiss-Prot: sp|Q03389|IF4E2_WHEAT Eukaryotic translation initiation factor isoform 4E-2; TrEMBL-Plants: tr|I3T1M7|I3T1M7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0008200 | 9 | ||
| – | Eukaryotic translation initiation factor 4E; TAIR: AT4G18040.1 eukaryotic translation initiation factor 4E; Swiss-Prot: sp|O23252|IF4E1_ARATH Eukaryotic translation initiation factor 4E-1; TrEMBL-Plants: tr|K0P2S0|K0P2S0_ARAHY Eukaryotic translation initiation factor 4E; Found in the gene: LotjaGi6g1v0314500 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 14.29 |