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IPR020618 is a Adenylate kinase isoenzyme 6.
<p>Adenylate kinase isoenzyme 6 (AK6) is a broad-specificity nucleoside monophosphate (NMP) kinase that catalyses the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates [[cite:PUB00030703]]. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. It has also ATPase activity and may have a role in nuclear energy homeostasis. AK6 is involved in regulation of Cajal body (CB) formation [[cite:PUB00068768], [cite:PUB00056952]].</p> <p>This entry also includes related putative adenylate kinases from archaea.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Adenylate kinase activity | Catalysis of the reaction: ATP + AMP = 2 ADP. | ||
Molecular function | ATP binding | Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: adenylate kinase isoenzyme 6-like [Cicer arietinum] gi|502141626|ref|XP_004504569.1| | 8 | ||
– | Adenylate kinase; TAIR: AT5G60340.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9FJI1|KAD6_ARATH Adenylate kinase isoenzyme 6 homolog; TrEMBL-Plants: tr|I3T9E6|I3T9E6_LOTJA Adenylate kinase isoenzyme 6 homolog; Found in the gene: LotjaGi1g1v0055900 | 9 | ||
– | Adenylate kinase; TAIR: AT5G60340.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9FJI1|KAD6_ARATH Adenylate kinase isoenzyme 6 homolog; TrEMBL-Plants: tr|I3T9E6|I3T9E6_LOTJA Adenylate kinase isoenzyme 6 homolog; Found in the gene: LotjaGi1g1v0055900 | 9 | ||
– | Adenylate kinase; TAIR: AT5G60340.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9FJI1|KAD6_ARATH Adenylate kinase isoenzyme 6 homolog; TrEMBL-Plants: tr|I3T9E6|I3T9E6_LOTJA Adenylate kinase isoenzyme 6 homolog; Found in the gene: LotjaGi1g1v0055900 | 9 | ||
– | Adenylate kinase; TAIR: AT5G60340.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9FJI1|KAD6_ARATH Adenylate kinase isoenzyme 6 homolog; TrEMBL-Plants: tr|I3T9E6|I3T9E6_LOTJA Adenylate kinase isoenzyme 6 homolog; Found in the gene: LotjaGi1g1v0142500 | 8 | ||
– | Adenylate kinase; TAIR: AT5G60340.1 P-loop containing nucleoside triphosphate hydrolases superfamily protein; Swiss-Prot: sp|Q9FJI1|KAD6_ARATH Adenylate kinase isoenzyme 6 homolog; TrEMBL-Plants: tr|I3T9E6|I3T9E6_LOTJA Adenylate kinase isoenzyme 6 homolog; Found in the gene: LotjaGi1g1v0142500 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
SSF52540 | SUPERFAMILY | 1 | 16.67 |