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IPR021726 is a THO complex, subunitTHOC2, N-terminal.
<p>The THO/TREX complex is the transcription- and export-related complex associated with spliceosomes that preferentially deal with spliced mRNAs as opposed to unspliced mRNAs. Thoc2 plays a role in RNA polymerase II (RNA pol II)-dependent transcription and is required for the stability of DNA repeats [[cite:PUB00018266]]. In humans, the TRE complex is comprised of the exon-junction-associated proteins Aly/REF and UAP56 together with the THO proteins THOC1 (hHpr1/p84), Thoc2 (hRlr1), THOC3 (hTex1), THOC5 (fSAP79), THOC6 (fSAP35), and THOC7 (fSAP24). Although much evidence indicates that the function of the TREX complex as an adaptor between the mRNA and components of the export machinery is conserved among eukaryotes, in Drosophila the majority of mRNAs can be exported from the nucleus independently of the THO complex [[cite:PUB00053541]].</p> <p>This entry represents a conserved domain found towards the N terminus of these proteins.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: THO complex subunit 2-like [Glycine max] gi|356513026|ref|XP_003525215.1| | 11 | ||
| – | PREDICTED: THO complex subunit 2-like [Glycine max] gi|356513026|ref|XP_003525215.1| | 10 | ||
| – | THO complex subunit 2; TAIR: AT1G24706.7 THO2; Swiss-Prot: sp|F4IAT2|THOC2_ARATH THO complex subunit 2; TrEMBL-Plants: tr|I1K5H3|I1K5H3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0459500 | 11 | ||
| – | THO complex subunit 2; TAIR: AT1G24706.7 THO2; Swiss-Prot: sp|F4IAT2|THOC2_ARATH THO complex subunit 2; TrEMBL-Plants: tr|I1K5H3|I1K5H3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0459500 | 11 | ||
| – | THO complex subunit 2; TAIR: AT1G24706.7 THO2; Swiss-Prot: sp|F4IAT2|THOC2_ARATH THO complex subunit 2; TrEMBL-Plants: tr|I1K5H3|I1K5H3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0459500 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 20.00 |