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IPR022175 is a BCAS3 domain.
<p>This domain is found towards the C-terminal of BCAS3 and ATG18-like proteins from plants. In BCAS3, this domain seems to be important for PHAF1 interactions [[cite:PUB00097858]].</p> <p>This entry includes BCAS3 microtubule associated cell migration factor (BCAS3) from animals and AT18F/G/H from Arabidopsis. BCAS3 is a microtubule associated cell migration factor that has been linked to the development of breast cancer and angiogenesis [[cite:PUB00089259]]. It forms a complex with PHAF1 and associates with the preautophagosomal structure during both non-selective and selective autophagy [[cite:PUB00097858]].</p> <p>AT18F/G/H are linked to autophagy [[cite:PUB00098125]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: autophagy-related protein 18g-like isoform X2 [Cicer arietinum] gi|502118016|ref|XP_004496059.1| | 11 | ||
| – | Autophagy-related protein [Medicago truncatula] gi|357452691|ref|XP_003596622.1| | 11 | ||
| – | PREDICTED: autophagy-related protein 18h-like isoform X3 [Cicer arietinum] gi|502117260|ref|XP_004495759.1| | 11 | ||
| – | Breast carcinoma-amplified sequence 3 like; TAIR: AT1G03380.1 yeast autophagy 18 G-like protein; Swiss-Prot: sp|Q8GUL1|AT18G_ARATH Autophagy-related protein 18g; TrEMBL-Plants: tr|A0A0B2SF76|A0A0B2SF76_GLYSO Breast carcinoma-amplified sequence 3 like; Found in the gene: LotjaGi1g1v0732300 | 12 | ||
| – | Breast carcinoma-amplified sequence 3 like; TAIR: AT5G54730.1 yeast autophagy 18 F-like protein; Swiss-Prot: sp|Q9FH32|AT18F_ARATH Autophagy-related protein 18f; TrEMBL-Plants: tr|I1M3I2|I1M3I2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0235400 | 11 | ||
| – | Breast carcinoma amplified sequence 3 protein; TAIR: AT1G54710.1 autophagy 18h-like protein; Swiss-Prot: sp|Q8H1Q5|AT18H_ARATH Autophagy-related protein 18h; TrEMBL-Plants: tr|A0A072VNS1|A0A072VNS1_MEDTR Breast carcinoma amplified sequence 3 protein; Found in the gene: LotjaGi5g1v0218000 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |