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IPR022369 is a Integral membrane protein TerC, riboswitch-linked.
<p>This entry represents a subset of TerC proteins which are mostly encoded on genes preceded by a structured RNA element known as the yybP-ykoY leader. The yybP-ykoY leader (also known as SraF) may function in the regulation of these genes as riboswitch [[cite:PUB00053669]]. This entry also includes the putative membrane-bound redox modulator Alx [[cite:PUB00009923]].</p> <p>A family containing a number of integral membrane proteins is named after TerC protein. TerC has been implicated in resistance to tellurium, and may be involved in efflux of tellurium ions. The tellurite-resistant Escherichia coli strain KL53 was found during testing of a group of clinical isolates for antibiotic and heavy metal ion resistance [[cite:PUB00008408]]. The determinant of the strain's tellurite resistance was located on a large conjugative plasmid, and analyses showed the genes terB, terC, terD and terE were essential for conservation of this resistance. Members of this family contain a number of conserved aspartates which may be involved in metal ion binding.</p> <p>A TerC homologue is known from the chloroplast thylakoid membrane from<i>Arabidopsis</i>which is important for thylakoid membrane biogenesis in the developing chloroplast [[cite:PUB00076704]]; it is required for insertion of proteins into the thylakoid membrane [[cite:PUB00085185]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | TerC integral membrane domain-containing protein isoform 2 [Theobroma cacao] gi|508715788|gb|EOY07685.1| | 10 | ||
| – | Protein pigment defective 149 [Arabidopsis thaliana] gi|18416778|ref|NP_568257.1| | 9 | ||
| – | Integral membrane protein, TerC family protein; TAIR: AT5G12130.1 integral membrane TerC family protein; Swiss-Prot: sp|F4JZG9|TERC_ARATH Thylakoid membrane protein TERC, chloroplastic; TrEMBL-Plants: tr|A0A0L9T9C8|A0A0L9T9C8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi5g1v0072300 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 33.33 |