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IPR023241

Source: InterPro

Description

IPR023241 is a FAM175 family, plant.

<p>This entry represents the plant members of FAM175.</p> <p>Members of protein family FAM175 include the BRCA1-A complex subunit Abraxas 1 [[cite:PUB00054085], [cite:PUB00054086]], BRISC complex subunit Abraxas 2 or Abro1 (Abraxas brother protein 1) [[cite:PUB00054087], [cite:PUB00054088]], and uncharacterised plant proteins.</p> <p>It is thought that BRCA1-A complex subunit Abraxas acts as a central scaffold protein responsible for assembling the various components of the BRCA1-A complex, and mediates recruitment of BRCA1 [[cite:PUB00054085], [cite:PUB00054086]]. Similarly, Abro1 probably acts as a scaffold facilitating assembly of the various components of BRISC [[cite:PUB00054087]] - the protein does not interact with BRCA1, but binds polyubiquitin [[cite:PUB00054088]]. The primary sequences of these proteins contain an MPN-like domain [[cite:PUB00054088]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj0g3v0223749.1
– Uncharacterized protein isoform 1 [Theobroma cacao] gi|508715176|gb|EOY07073.1|
Domains
5
Lj0g3v0356789.1
– PREDICTED: BRCA1-A complex subunit Abraxas [Vitis vinifera] gi|225439544|ref|XP_002263634.1|
Domains
5
LotjaGi3g1v0199600.1
– BRCA1-A complex subunit Abraxas; TAIR: AT3G08780.1 BRISC complex subunit Abro1-like protein; Swiss-Prot: sp|Q6P4W0|F175B_XENTR BRISC complex subunit Abro1; TrEMBL-Plants: tr|I1J7I2|I1J7I2_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0199600
Domains
6

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR31728:SF5 PANTHER 1 33.33