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IPR023509 is a D-aminoacyl-tRNA deacylase-like superfamily.
<p>D-tyrosyl-tRNA(Tyr) deacylase (DTD), also known as D-aminoacyl-tRNA deacylase, is an editing enzyme that removes D-amino acids from mischarged tRNAs. Structural studies have shown various different modes of D-amino acid recognition by DTDs, suggesting an inherent plasticity that can accommodate all d-amino acids. DTDs are essentially inactive toward L-aa-tRNAs [[cite:PUB00058619], [cite:PUB00097389]].</p> <p>This superfamily represents a DTD fold, consisting of a β-barrel closed on one side by a β-sheet lid [[cite:PUB00017393]]. The DTD fold is present across the domains of life in two different functional contexts: as an N-terminal editing domain of archaeal ThrRS (Threonyl-tRNA synthetase), which specifically removes noncognate L-serine mischarged on tRNAThr, and as a freestanding 'chiral proofreading' enzyme, which removes D-amino acids from tRNAs in bacteria and eukaryotes [[cite:PUB00088138]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: D-tyrosyl-tRNA(Tyr) deacylase-like [Glycine max] gi|356555390|ref|XP_003546015.1| | 9 | ||
| – | D-aminoacyl-tRNA deacylase; TAIR: AT4G18460.1 D-Tyr-tRNA(Tyr) deacylase family protein; Swiss-Prot: sp|Q54EY1|DTD_DICDI D-tyrosyl-tRNA(Tyr) deacylase; TrEMBL-Plants: tr|A0A0S3S2V1|A0A0S3S2V1_PHAAN D-tyrosyl-tRNA(Tyr) deacylase; Found in the gene: LotjaGi6g1v0326000 | 10 | ||
| – | D-aminoacyl-tRNA deacylase; TAIR: AT4G18460.1 D-Tyr-tRNA(Tyr) deacylase family protein; Swiss-Prot: sp|Q54EY1|DTD_DICDI D-tyrosyl-tRNA(Tyr) deacylase; TrEMBL-Plants: tr|A0A0L9VFL8|A0A0L9VFL8_PHAAN D-tyrosyl-tRNA(Tyr) deacylase; Found in the gene: LotjaGi6g1v0326000 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00256 | TIGRFAM | 1 | 33.33 |