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IPR024224

Source: InterPro

Description

IPR024224 is a DENND6.

<p>The DENND6 family of proteins includes DENND6A and B. They act as guanine nucleotide exchange factors (GEF) for RAB14 [[cite:PUB00066797]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0017112
Molecular function Rab guanyl-nucleotide exchange factor activity Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rab family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Subterm of

Associated Lotus transcripts 5

Transcript Name Description Predicted domains Domain count
Lj0g3v0331549.1
– PREDICTED: protein FAM116A-like [Glycine max] gi|356510584|ref|XP_003524017.1|
Domains
4
Lj0g3v0331549.2
– PREDICTED: protein FAM116A-like [Glycine max] gi|356510584|ref|XP_003524017.1|
Domains
4
LotjaGi1g1v0204000.1
– Protein DENND6A; TAIR: AT1G73930.1 polarity axis stabilization protein; Swiss-Prot: sp|Q8IWF6|DEN6A_HUMAN Protein DENND6A; TrEMBL-Plants: tr|K7KK42|K7KK42_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0204000
Domains
6
LotjaGi1g1v0204000.2
– Protein DENND6A; TAIR: AT1G73930.1 polarity axis stabilization protein; Swiss-Prot: sp|Q8IWF6|DEN6A_HUMAN Protein DENND6A; TrEMBL-Plants: tr|K7KK42|K7KK42_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0204000
Domains
6
LotjaGi1g1v0204000.3
– Protein DENND6A; TAIR: AT1G73930.1 polarity axis stabilization protein; Swiss-Prot: sp|Q8IWF6|DEN6A_HUMAN Protein DENND6A; TrEMBL-Plants: tr|K7KK42|K7KK42_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0204000
Domains
6

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
PTHR13677:SF0 PANTHER 1 20.00