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IPR026635

Source: InterPro

Description

IPR026635 is a Protein-lysine N-methyltransferase Efm4/METTL10.

<p><i>Saccharomyces cerevisiae</i>Efm4 (also known as See1) is a lysine methyltransferase that dimethylates eukaryotic elongation factor 1A (eEF1A1) at lysine residues [[cite:PUB00060864]]. It may also play a role in intracellular transport [[cite:PUB00060865]]. This entry also includes methyltransferase-like protein 10 (METTL10; EEF1A lysine methyltransferase 2) from fish and mammals, which catalyzes the trimethylation of EEF1A at 'Lys-318' [[cite:PUB00085162]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0008168
Molecular function Methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj1g3v3244620.1
– PREDICTED: methyltransferase-like protein 10-like [Glycine max] gi|356569031|ref|XP_003552710.1|
Domains
11
LotjaGi1g1v0545000.1
– Methyltransferase, putative; TAIR: AT1G66680.1 S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Swiss-Prot: sp|Q5JPI9|MET10_HUMAN Protein-lysine N-methyltransferase METTL10; TrEMBL-Plants: tr|A0A151TD67|A0A151TD67_CAJCA Protein-lysine N-methyltransferase KK1_019616; Found in the gene: LotjaGi1g1v0545000
Domains
11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00